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FPR3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649070

Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a… More details

$895 / 0.2 mL +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
FPR3, Polyclonal Antibody
Full Product Name
FPR3, CT (FPR3, FPRH1, FPRL2, N-formyl peptide receptor 3, FMLP-related receptor II, Formyl peptide receptor-like 2)
Product Gene Name
Product Synonym Names
Anti -FPR3, CT (FPR3, FPRH1, FPRL2, N-formyl peptide receptor 3, FMLP-related receptor II, Formyl peptide receptor-like 2)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
46,553 Da
Chromosome Location
Chromosome: XIII; NC_001145.3 (120089..121324, complement). Location: chromosome: XIII
3D Structure
ModBase 3D Structure for P38911
Immunogen
FPR3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 321-351 amino acids from the C-terminal region of human FPR3.

Product Categories/Family for anti-FPR3 antibody

Applications Tested/Suitable for anti-FPR3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-FPR3 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-FPR3 antibody

FPR3 Antibody (C-term) western blot analysis in ZR-75-1 cell line lysates (35ug/lane).This demonstrates the FPR3 antibody detected the FPR3 protein (arrow).
Rabbit Anti-FPR3 Polyclonal Antibody – Cat# MBS649070

Other Notes

Small volumes of anti-FPR3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FPR3 purchase

MBS649070 is an antibody targeting FPR3. Also known as FPR3, CT (FPR3, FPRH1, FPRL2, N-formyl peptide receptor 3, FMLP-related receptor II, Formyl peptide receptor-like 2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FPR3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
FK506-binding nuclear protein
NCBI Official Symbol
FPR3
NCBI Official Synonym Symbols
NPI46
UniProt Protein Name
FK506-binding nuclear protein
UniProt Synonym Protein Names
FKBP-70; Nucleolar proline isomerase; Peptidyl-prolyl cis-trans isomerase; PPIase; Proline rotamase
UniProt Gene Name
FPR3
UniProt Synonym Gene Names
NPI46; PPIase
UniProt Entry Name
FKBP3_YEAST
NCBI Protein Information
peptidylprolyl isomerase FPR3

UniProt Comments for FPR3

Function: PPIases accelerate the folding of proteins. FK506- and rapamycin-binding protein. Specifically binds nuclear localization sequences. May be involved in the assembly or folding of ribosomal proteins.

Catalytic activity: Peptidylproline (omega=180) = peptidylproline (omega=0).

Enzyme regulation: Inhibited by both FK506 and rapamycin.

Subunit structure: Interacts with NOP53. Ref.9

Subcellular location: Nucleus › nucleolus.

Post-translational modification: Phosphorylated at tyrosine and dephosphorylated by the phosphotyrosine-specific phosphoprotein phosphatase PTP1. Ref.7

Miscellaneous: Present with 9490 molecules/cell in log phase SD medium.

Sequence similarities: Belongs to the FKBP-type PPIase family. FKBP3/4 subfamily.Contains 1 PPIase FKBP-type domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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