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Nucleoside Diphosphate Kinase 6 (NDK6) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6490811

MBS6490811 is an antibody targeting NDK6. Also known as Nucleoside Diphosphate Kinase 6, NT (NDP Kinase 6, NDK 6, Inhibitor of p53-induced Apoptosis-alpha, IPIA-alpha, nm23-H6, NME6) (MaxLight 550). Reactive in Human. Host: Rabbit. More details

$1060 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Nucleoside Diphosphate Kinase 6 (NDK6), Polyclonal Antibody
Full Product Name
Nucleoside Diphosphate Kinase 6, NT (NDP Kinase 6, NDK 6, Inhibitor of p53-induced Apoptosis-alpha, IPIA-alpha, nm23-H6, NME6) (MaxLight 550)
Product Gene Name
anti-NDK6 antibody
Product Synonym Names
Non-metastatic Cells 6; Protein Expressed in (Nucleoside-diphosphate Kinase); EC=2.7.4.6
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight550.
Purity/Purification
Purified by Protein G Affinity Chromatography.
Specificity
Recognizes human NME6.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight550 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
21,142 Da
Chromosome Location
Chromosome: 3; NC_000003.11 (48335576..48342848, complement). Location: 3p21
OMIM
608294
3D Structure
ModBase 3D Structure for O75414
Immunogen
Synthetic peptide selected from the N-terminal region of human NME6 (KLH).
Conjugate
MaxLight550
Note
Preservative Free

Product Categories/Family for anti-NDK6 antibody

Antibodies; Protein Kinases
Applications Tested/Suitable for anti-NDK6 antibody
Western Blot (WB), FLISA
Application Notes for anti-NDK6 antibody
WB: 1:100-1:500
FLISA: 1:1,000
Applications are based on unconjugated antibody.

Product References and Citations for anti-NDK6 antibody

1. Strausberg, R.L., et al., Proc. Natl. Acad. Sci. USA 99(26):16899-16903 (2002). 2. Mehus, J.G., et al., Hum. Genet. 104(6):454-459 (1999).

Other Notes

Small volumes of anti-NDK6 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NDK6. It may not necessarily be applicable to this product.

NCBI GI #
5031951
NCBI GeneID
10201
NCBI Accession #
NP_005784.1
UniProt Primary Accession #
O75414
UniProt Secondary Accession #
Q53HM5; Q96E73; Q9BQ63; B4DGW7; B4DM99
UniProt Related Accession #
O75414
GenBank Nucleotide #
NM_005793.3
NCBI Official Full Name
nucleoside diphosphate kinase 6
NCBI Official Synonym Full Names
non-metastatic cells 6, protein expressed in (nucleoside-diphosphate kinase)
NCBI Official Symbol
NME6
NCBI Official Synonym Symbols
NDK 6; NM23-H6; IPIA-ALPHA
UniProt Protein Name
Nucleoside diphosphate kinase 6
UniProt Synonym Protein Names
Inhibitor of p53-induced apoptosis-alpha; IPIA-alpha; nm23-H6
Protein Family
Nucleoside diphosphate kinase
UniProt Gene Name
NME6
UniProt Entry Name
NDK6_HUMAN
NCBI Protein Information
nucleoside diphosphate kinase 6; NDP kinase 6; OTTHUMP00000164810; OTTHUMP00000210736; OTTHUMP00000210737; OTTHUMP00000210738; OTTHUMP00000210741; OTTHUMP00000210742; OTTHUMP00000210744; OTTHUMP00000210745; inhibitor of p53-induced apoptosis-alpha

NCBI Summary for NDK6

Nucleoside diphosphate (NDP) kinases (EC 2.7.4.6), such as NME6, are ubiquitous enzymes that catalyze transfer of gamma-phosphates, via a phosphohistidine intermediate, between nucleoside and dioxynucleoside tri- and diphosphates (Mehus et al., 1999 [PubMed 10453732]).[supplied by OMIM]

UniProt Comments for NDK6

NME6: Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis. Belongs to the NDK family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Nucleotide Metabolism - purine; Nucleotide Metabolism - pyrimidine; EC 2.7.4.6; Kinase, other; Kinase, nucleoside diphosphate; Other group; NDK family

Chromosomal Location of Human Ortholog: 3p21

Cellular Component: mitochondrion

Molecular Function: metal ion binding; nucleoside diphosphate kinase activity; ATP binding

Biological Process: GTP biosynthetic process; CTP biosynthetic process; apoptosis; UTP biosynthetic process; negative regulation of mitosis; nucleoside diphosphate phosphorylation; negative regulation of cell growth
Show more

Research Articles on NDK6

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NDK6 antibody

 Products by Pathway  Pathway Diagram
 Metabolic Pathways antibodies  Metabolic Pathways Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Purine Metabolism Pathway antibodies  Purine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram
 Pyrimidine Metabolism Pathway antibodies  Pyrimidine Metabolism Pathway Diagram

Organs/Tissues associated with anti-NDK6 antibody

 Organ/Tissue Name  Pubmed Publications
 Prostate Antibodies  >1 publications with NDK6 and Prostate
 Kidney Antibodies  >1 publications with NDK6 and Kidney
 Intestine Antibodies  >1 publications with NDK6 and Intestine
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