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UGT1A9 Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649102

MBS649102 is an antibody targeting UGT1A9. Also known as UGT1A9 (UDP-glucuronosyltransferase 1A9, UDP-glucuronosyltransferase 1-9, UDPGT 1-9, UGT1*9, UGT1-09, UGT1.9, UDP-glucuronosyltransferase 1-I, UGT-1I, UGT1I, GNT1, lugP4, UGT1). Reactive in Human. Host:… More details

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Sample Manual Insert View PDF
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Testing Data View PDF
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Product Overview

Online Datasheet in PDF
Product Name
UGT1A9, Polyclonal Antibody
Full Product Name
UGT1A9 (UDP-glucuronosyltransferase 1A9, UDP-glucuronosyltransferase 1-9, UDPGT 1-9, UGT1*9, UGT1-09, UGT1.9, UDP-glucuronosyltransferase 1-I, UGT-1I, UGT1I, GNT1, lugP4, UGT1)
Product Gene Name
Product Synonym Names
Anti -UGT1A9 (UDP-glucuronosyltransferase 1A9, UDP-glucuronosyltransferase 1-9, UDPGT 1-9, UGT1*9, UGT1-09, UGT1.9, UDP-glucuronosyltransferase 1-I, UGT-1I, UGT1I, GNT1, lugP4, UGT1)
Immunogen Sequence
MACTGWTSPL PLCVCLLLTC GFAEAGKLLV VPMDGSHWFT MRSVVEKLIL RGHEVVVVMP EVSWQLGRSL NCTVKTYSTS YTLEDLDREF KAFAHAQWKA QVRSIYSLLM GSYNDIFDLF FSNCRSLFKD KKLVEYLKES SFDAVFLDPF DNCGLIVAKY FSLPSVVFAR GILCHYLEEG AQCPAPLSYV PRILLGFSDA MTFKERVRNH IMHLEEHLLC HRFFKNALEI ASEILQTPVT EYDLYSHTSI WLLRTDFVLD YPKPVMPNMI FIGGINCHQG KPLPMEFEAY INASGEHGIV VFSLGSMVSE IPEKKAMAIA DALGKIPQTV LWRYTGTRPS NLANNTILVK WLPQNDLLGH PMTRAFITHA GSHGVYESIC NGVPMVMMPL FGDQMDNAKR METKGAGVTL NVLEMTSEDL ENALKAVIND KSYKENIMRL SSLHKDRPVE PLDLAVFWVE FVMRHKGAPH LRPAAHDLTW YQYHSLDVIG FLLAVVLTVA FITFKCCAYG YRKCLGKKGR VKKAHKSKTH
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human UGT1A9.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
59,941 Da
Chromosome Location
Chromosome: 2; NC_000002.11 (234580544..234681951). Location: 2q37
OMIM
191740
3D Structure
ModBase 3D Structure for O60656
Immunogen
Full length human UGT1A9, aa1-530 (NP_066307.1).

Product Categories/Family for anti-UGT1A9 antibody

Applications Tested/Suitable for anti-UGT1A9 antibody
Western Blot (WB), Immunohistochemistry (IHC)
Application Notes for anti-UGT1A9 antibody
Suitable for use in Western Blot and Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 3ug/ml

Western Blot (WB) of anti-UGT1A9 antibody

Western Blot analysis of UGT1A9 expression in human liver using anti-UGT1A9 antibody MBS649102.
Mouse Anti-UGT1A9 Polyclonal Antibody – Cat# MBS649102

Western Blot (WB) of anti-UGT1A9 antibody

Western Blot analysis of UGT1A9 expression in transfected 293T cell line using anti-UGT1A9 antibody MBS649102: Lane 1: UGT1A9 transfected lysate (58.3kD) Lane 2: Non-transfected lysate
Mouse Anti-UGT1A9 Polyclonal Antibody, Western Blot (WB) – Cat# MBS649102

Immunohistochemistry (IHC) of anti-UGT1A9 antibody

IHC staining of formalin-fixed paraffin-embedded human small Intestine using anti-UGT1A9 antibody MBS649102 at 3ug/ml. Peroxidase-conjugated anti-mouse secondary antibody was used.
Mouse Anti-UGT1A9 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS649102

Other Notes

Small volumes of anti-UGT1A9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UGT1A9. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
UDP-glucuronosyltransferase 1-9
NCBI Official Synonym Full Names
UDP glucuronosyltransferase 1 family, polypeptide A9
NCBI Official Symbol
UGT1A9
NCBI Official Synonym Symbols
LUGP4; UDPGT; UGT1I; HLUGP4; UGT-1I; UGT1-9; UGT1.9; UGT1AI; UGT1-09; UDPGT 1-9
UniProt Protein Name
UDP-glucuronosyltransferase 1-9
UniProt Synonym Protein Names
UDP-glucuronosyltransferase 1-I; UGT-1I; UGT1I; UDP-glucuronosyltransferase 1A9; lugP4
UniProt Gene Name
UGT1A9
UniProt Synonym Gene Names
GNT1; UGT1; UDPGT 1-9; UGT1*9; UGT1-09; UGT1.9; UGT-1I; UGT1I
UniProt Entry Name
UD19_HUMAN
NCBI Protein Information
UDP-glucuronosyltransferase 1-9; UDP-glucuronosyltransferase 1-I; UDP-glucuronosyltransferase 1A9; UDP glycosyltransferase 1 family, polypeptide A9

NCBI Summary for UGT1A9

This gene encodes a UDP-glucuronosyltransferase, an enzyme of the glucuronidation pathway that transforms small lipophilic molecules, such as steroids, bilirubin, hormones, and drugs, into water-soluble, excretable metabolites. This gene is part of a complex locus that encodes several UDP-glucuronosyltransferases. The locus includes thirteen unique alternate first exons followed by four common exons. Four of the alternate first exons are considered pseudogenes. Each of the remaining nine 5' exons may be spliced to the four common exons, resulting in nine proteins with different N-termini and identical C-termini. Each first exon encodes the substrate binding site, and is regulated by its own promoter. The enzyme encoded by this gene is active on phenols. [provided by RefSeq, Jul 2008]
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UniProt Comments for UGT1A9

Function: UDPGT is of major importance in the conjugation and subsequent elimination of potentially toxic xenobiotics and endogenous compounds. This isoform has specificity for phenols.

Catalytic activity: UDP-glucuronate + acceptor = UDP + acceptor beta-D-glucuronoside.

Subcellular location: Microsome. Endoplasmic reticulum membrane; Single-pass membrane protein

Potential.

Tissue specificity: Liver.

Sequence similarities: Belongs to the UDP-glycosyltransferase family.

Sequence caution: The sequence AAB19791.2 differs from that shown. Reason: Frameshift at positions 59 and 82.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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