• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

CYTH3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649194

This gene encodes a member of the PSCD (pleckstrin homology, Sec7 and coiled-coil domains) family. PSCD family members have identical structural organization that consists of an N-terminal coiled-coil motif, a central Sec7 domain, and a C-terminal pleckstrin… More details

$895 / 0.2 mL +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CYTH3, Polyclonal Antibody
Full Product Name
CYTH3, CT (CYTH3, ARNO3, GRP1, PSCD3, Cytohesin-3, ARF nucleotide-binding site opener 3, General receptor of phosphoinositides 1, PH, SEC7 and coiled-coil domain-containing protein 3)
Product Gene Name
anti-CYTH3 antibody
Product Synonym Names
Anti -CYTH3, CT (CYTH3, ARNO3, GRP1, PSCD3, Cytohesin-3, ARF nucleotide-binding site opener 3, General receptor of phosphoinositides 1, PH, SEC7 and coiled-coil domain-containing protein 3)
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Human, mouse
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
46,349 Da
Chromosome Location
Chromosome: 7; NC_000007.13 (6201407..6312242, complement). Location: 7p22.1
OMIM
605081
3D Structure
ModBase 3D Structure for O43739
Immunogen
CYTH3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 371~400 amino acids from the C-terminal region of human CYTH3.

Product Categories/Family for anti-CYTH3 antibody

Antibodies; Abs to Binding Proteins
Applications Tested/Suitable for anti-CYTH3 antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-CYTH3 antibody
Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Western Blot (WB) of anti-CYTH3 antibody

Western blot analysis of CYTH3 Antibody (C-term) in Hela cell line lysates (35ug/lane). CYTH3 (arrow) was detected using the purified Pab;
Rabbit Anti-CYTH3 Polyclonal Antibody – Cat# MBS649194

Western Blot (WB) of anti-CYTH3 antibody

Western blot analysis of CYTH3 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). CYTH3 (arrow) was detected using the purified Pab.
Rabbit Anti-CYTH3 Polyclonal Antibody, Western Blot (WB) – Cat# MBS649194

Other Notes

Small volumes of anti-CYTH3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CYTH3 purchase

MBS649194 is an antibody targeting CYTH3. Also known as CYTH3, CT (CYTH3, ARNO3, GRP1, PSCD3, Cytohesin-3, ARF nucleotide-binding site opener 3, General receptor of phosphoinositides 1, PH, SEC7 and coiled-coil domain-containing protein 3). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CYTH3. It may not necessarily be applicable to this product.

NCBI GI #
14198263
NCBI GeneID
9265
NCBI Accession #
AAH08191.1
UniProt Primary Accession #
O43739
UniProt Secondary Accession #
A4D2N8
UniProt Related Accession #
O43739
NCBI Official Full Name
CYTH3 protein
NCBI Official Synonym Full Names
cytohesin 3
NCBI Official Symbol
CYTH3
NCBI Official Synonym Symbols
GRP1; ARNO3; PSCD3
UniProt Protein Name
Cytohesin-3
UniProt Synonym Protein Names
ARF nucleotide-binding site opener 3; Protein ARNO3; General receptor of phosphoinositides 1; Grp1; PH, SEC7 and coiled-coil domain-containing protein 3
Protein Family
Cytohesin
UniProt Gene Name
CYTH3
UniProt Synonym Gene Names
ARNO3; GRP1; PSCD3; Protein ARNO3; Grp1
UniProt Entry Name
CYH3_HUMAN
NCBI Protein Information
cytohesin-3; ARF nucleotide-binding site opener 3; general receptor of phosphoinositides 1; pleckstrin homology, Sec7 and coiled-coil domains 3; PH, SEC7 and coiled-coil domain-containing protein 3

UniProt Comments for CYTH3

Function: Promotes guanine-nucleotide exchange on ARF1. Promotes the activation of ARF through replacement of GDP with GTP.

Subunit structure: Binds via its PH domain to the inositol head group of phosphatidylinositol 3,4,5-trisphosphate with high affinity. Interacts with GRASP

By similarity.

Subcellular location: Cell membrane Ref.7.

Tissue specificity: Almost absent from liver, thymus and peripheral blood lymphocytes.

Sequence similarities: Contains 1 PH domain.Contains 1 SEC7 domain.
Show more

Research Articles on CYTH3

1. The PH domains of cytohesin 2/ARNO and cytohesin 3/GRP1 are responsible for the differential effects of these proteins on cell adhesion to fibronectin.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CYTH3 antibody

 Reference Product  PubMed Publications
 ARF1 antibody  >1 publications with CYTH3 and ARF1
 ARF6 antibody  >1 publications with CYTH3 and ARF6

Pathways associated with anti-CYTH3 antibody

 Products by Pathway  Pathway Diagram
 Arf6 Signaling Events Pathway antibodies  Arf6 Signaling Events Pathway Diagram
 Class I PI3K Signaling Events Pathway antibodies  Class I PI3K Signaling Events Pathway Diagram
 Insulin Signaling Pathway antibodies  Insulin Signaling Pathway Diagram

Organs/Tissues associated with anti-CYTH3 antibody

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with CYTH3 and Muscle
 Embryonic Tissue Antibodies  >1 publications with CYTH3 and Embryonic Tissue
 Uterus Antibodies  >1 publications with CYTH3 and Uterus
 Placenta Antibodies  >1 publications with CYTH3 and Placenta
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000