Rabbit Anti-FARP1 Polyclonal Antibody – Cat# MBS649297

FARP1 Antibody (N-term) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the FARP1 antibody detected the FARP1 protein (arrow).

FARP1 Antibody – Rabbit Polyclonal

Name: FARP1 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS649297
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649297

This gene was originally isolated through subtractive hybridization due to its increased expression in differentiated chondrocytes versus dedifferentiated chondrocytes. The resulting protein contains a predicted ezrin-like domain, a Dbl homology domain, and a… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FARP1, Polyclonal Antibody

Full Product Name

FARP1, NT (FARP1, CDEP, PLEKHC2, FERM, RhoGEF and pleckstrin domain-containing protein 1, Chondrocyte-derived ezrin-like protein, Pleckstrin homology domain-containing family C member 2)

Product Gene Name

anti-FARP1 antibody

Product Synonym Names

Anti -FARP1, NT (FARP1, CDEP, PLEKHC2, FERM, RhoGEF and pleckstrin domain-containing protein 1, Chondrocyte-derived ezrin-like protein, Pleckstrin homology domain-containing family C member 2)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

118,633 Da

Chromosome Location

Chromosome: 13; NC_000013.10 (98794893..99102023). Location: 13q32.2

OMIM

602654

3D Structure

ModBase 3D Structure for Q9Y4F1

Immunogen

FARP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 61-90 amino acids from the N-terminal region of human FARP1.

Product Categories/Family for anti-FARP1 antibody

Antibodies; Abs to Pleckstrin Homology Proteins

Applications Tested/Suitable for anti-FARP1 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-FARP1 antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-FARP1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FARP1 purchase

MBS649297 is an antibody targeting FARP1. Also known as FARP1, NT (FARP1, CDEP, PLEKHC2, FERM, RhoGEF and pleckstrin domain-containing protein 1, Chondrocyte-derived ezrin-like protein, Pleckstrin homology domain-containing family C member 2). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for FARP1. It may not necessarily be applicable to this product.

NCBI GI #

47940452

NCBI GeneID

10160

NCBI Accession #

AAH71592.1

UniProt Primary Accession #

Q9Y4F1

UniProt Secondary Accession #

Q5JVI9; Q6IQ29

UniProt Related Accession #

Q9Y4F1

NCBI Official Full Name

FARP1 protein

NCBI Official Synonym Full Names

FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

NCBI Official Symbol

FARP1

NCBI Official Synonym Symbols

CDEP; PLEKHC2; PPP1R75

UniProt Protein Name

FERM, RhoGEF and pleckstrin domain-containing protein 1

UniProt Synonym Protein Names

Chondrocyte-derived ezrin-like protein; Pleckstrin homology domain-containing family C member 2

Protein Family

FERM, RhoGEF and pleckstrin domain-containing protein

UniProt Gene Name

FARP1

UniProt Synonym Gene Names

CDEP; PLEKHC2; PH domain-containing family C member 2

UniProt Entry Name

FARP1_HUMAN

NCBI Protein Information

FERM, RhoGEF and pleckstrin domain-containing protein 1; PH domain-containing family C member 2; chondrocyte-derived ezrin-like protein; protein phosphatase 1, regulatory subunit 75; pleckstrin homology domain-containing family C member 2

UniProt Comments for FARP1

Function: Functions as guanine nucleotide exchange factor for RAC1. May play a role in semaphorin signaling. Plays a role in the assembly and disassembly of dendritic filopodia, the formation of dendritic spines, regulation of dendrite length and ultimately the formation of synapses

By similarity.

Subunit structure: Interacts with CADM1. Interacts with RAC1

By similarity.

Subcellular location: Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cell junction › synapse. Cell junction › synapse › synaptosome

By similarity. Cytoplasm › cytosol

By similarity. Cell projection › filopodium

By similarity. Cell projection › dendrite

By similarity. Cell projection › dendritic spine

By similarity. Note: Recruited to the cell membrane via interaction with CADM1

By similarity.

Tissue specificity: Detected in cAMP-treated chondrocytes, but not in untreated chondrocytes. Detected in fetal brain, heart and spleen, and in adult testis, kidney and lung. Ref.1

Induction: Up-regulated in response to cAMP in cultured embryonic chondrocytes. Ref.1

Domain: Intramolecular interaction between the DH domain and the PH domains can stabilize the protein in an autoinhibited conformation. Ref.13

Sequence similarities: Contains 1 DH (DBL-homology) domain.Contains 1 FERM domain.Contains 2 PH domains.

Research Articles on FARP1

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-FARP1 antibody

Reference Product	PubMed Publications
RNF113B antibody	>1 publications with FARP1 and RNF113B
PLXNA4 antibody	>1 publications with FARP1 and PLXNA4

Pathways associated with anti-FARP1 antibody

Products by Pathway	Pathway Diagram
Regulation Of RhoA Activity Pathway antibodies	Regulation Of RhoA Activity Pathway Diagram

Diseases associated with anti-FARP1 antibody

Disease Name	Pubmed Publications
Aneuploidy Antibodies	>1 publications with FARP1 and Aneuploidy
Congenital Abnormalities Antibodies	>1 publications with FARP1 and Congenital Abnormalities

Organs/Tissues associated with anti-FARP1 antibody

Organ/Tissue Name	Pubmed Publications
Bone Antibodies	>1 publications with FARP1 and Bone
Eye Antibodies	>1 publications with FARP1 and Eye
Brain Antibodies	>1 publications with FARP1 and Brain