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CHERP Antibody – Mouse Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649326

MBS649326 is an antibody targeting CHERP. Also known as CHERP (DAN26, SCAF6, Calcium Homeostasis Endoplasmic Reticulum Protein, ERPROT 213-21, SR-related CTD-associated Factor 6). Reactive in Human. Host: Mouse. CHERP is involved in calcium homeostasis,… More details

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Product Overview

Online Datasheet in PDF
Product Name
CHERP, Polyclonal Antibody
Full Product Name
CHERP (DAN26, SCAF6, Calcium Homeostasis Endoplasmic Reticulum Protein, ERPROT 213-21, SR-related CTD-associated Factor 6)
Product Gene Name
anti-CHERP antibody
Product Synonym Names
Anti -CHERP (DAN26, SCAF6, Calcium Homeostasis Endoplasmic Reticulum Protein, ERPROT 213-21, SR-related CTD-associated Factor 6)
Immunogen Sequence
MTMEKQKDNP KFSFLFGGEF YSYYKCKLAL EQQQLICKQQ TPELEPAATM PPLPQPPLAP AAPIPPAQGA PSMDELIQQS QWNLQQQEQH LLALRQEQVT AAVAHAVEQQ MQKLLEETQL DMNEFDNLLQ PIIDTCTKDA ISAGKNWMFS NAKSPPHCEL MAGHLRNRIT ADGAHFELRL HLIYLINDVL HHCQRKQARE LLAALQKVVV PIYCTSFLAV EEDKQQKIAR LLQLWEKNGY FDDSIIQQLQ SPALGLGQYQ ATLINEYSSV VQPVQLAFQQ QIQTLKTQHE EFVTSLAQQQ QQQQQQQQQL QMPQMEAEVK ATPPPPAPPP APAPAPAIPP TTQPDDSKPP IQMPGSSEYE APGGVQDPAA AGPRGPGPHD QIPPNKPPWF DQPHPVAPWG QQQPPEQPPY PHHQGGPPHC PPWNNSHEGM WGEQRGDPGW NGQRDAPWNN QPDAAWNSQF EGPWNSQHEQ PPWGGGQREP PFRMQRPPHF RGPFPPHQQH PQFNQPPHPH NFNRFPPRFM QDDFPPRHPF ERPPYPHRFD YPQGDFPAEM GPPHHHPGHR MPHPGINEHP PWAGPQHPDF GPPPHGFNGQ PPHMRRQGPP HINHDDPSLV PNVPYFDLPA GLMAPLVKLE DHEYKPLDPK DIRLPPPMPP SERLLAAVEA FYSPPSHDRP RNSEGWEQNG LYEFFRAKMR ARRRKGQEKR NSGPSRSRSR SKSRGRSSSR SNSRSSKSSG SYSRSRSRSC SRSYSRSRSR SRSRSRSSRS RSRSQSRSRS KSYSPGRRRR SRSRSPTPPS SAGLGSNSAP PIPDSRLGEE NKGHQMLVKM GWSGSGGLGA KEQGIQDPIK GGDVRDKWDQ YKGVGVALDD PYENYRRNKS YSFIARMKAR DECK
Clonality
Polyclonal
Isotype
IgG
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human CHERP.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
103,702 Da
Chromosome Location
Chromosome: 19; NC_000019.9 (16628700..16653341, complement). Location: 19p13.1
3D Structure
ModBase 3D Structure for Q8IWX8
Immunogen
Full-length human CHERP, aa1-884 (AAH21294.1).

Product Categories/Family for anti-CHERP antibody

Antibodies; Abs to Proteins
Applications Tested/Suitable for anti-CHERP antibody
Western Blot (WB)
Application Notes for anti-CHERP antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-CHERP antibody

CHERP polyclonal antibody. Western Blot analysis of CHERP expression in Jurkat.
Mouse Anti-CHERP Polyclonal Antibody – Cat# MBS649326

Western Blot (WB) of anti-CHERP antibody

Western Blot analysis of CHERP expression in transfected 293T cell line by CHERP polyclonal antibody. Lane 1: CHERP transfected lysate (100kD). Lane 2: Non-transfected lysate.
Mouse Anti-CHERP Polyclonal Antibody, Western Blot (WB) – Cat# MBS649326

Other Notes

Small volumes of anti-CHERP antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CHERP. It may not necessarily be applicable to this product.

NCBI GI #
119226260
NCBI GeneID
10523
NCBI Accession #
NP_006378.3
UniProt Primary Accession #
Q8IWX8
UniProt Secondary Accession #
O00302; Q4G0Y5; Q8WU30; Q99492
UniProt Related Accession #
Q8IWX8
GenBank Nucleotide #
NM_006387.5
NCBI Official Full Name
calcium homeostasis endoplasmic reticulum protein
NCBI Official Synonym Full Names
calcium homeostasis endoplasmic reticulum protein
NCBI Official Symbol
CHERP
NCBI Official Synonym Symbols
SRA1; DAN16; SCAF6
UniProt Protein Name
Calcium homeostasis endoplasmic reticulum protein
UniProt Synonym Protein Names
ERPROT 213-21; SR-related CTD-associated factor 6
Protein Family
Calcium homeostasis endoplasmic reticulum protein
UniProt Gene Name
CHERP
UniProt Synonym Gene Names
DAN26; SCAF6
UniProt Entry Name
CHERP_HUMAN
NCBI Protein Information
calcium homeostasis endoplasmic reticulum protein; ERPROT213-21; ERPROT 213-21; protein with polyglutamine repeat; SR-related CTD associated factor 6; SR-related CTD-associated factor 6

UniProt Comments for CHERP

Function: Involved in calcium homeostasis, growth and proliferation. Ref.5 Ref.7

Subcellular location: Cytoplasm. Cytoplasm › perinuclear region. Endoplasmic reticulum. Note: Distributed throughout the cytoplasm and also localizes to the perinuclear region of both human erythroleukemia (HEL) cells and Jurkat cells. Colocalizes with ITPR1. Ref.5 Ref.6 Ref.7

Tissue specificity: Expressed in brain, placenta, lung, liver, kidney, pancreas, cardiac and skeletal muscle, and in cultured HEL and Dami cells. Ref.5

Sequence similarities: Contains 1 CID domain.Contains 1 G-patch domain.Contains 1 SURP motif repeat.

Sequence caution: The sequence AAB53327.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH21294.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence CAA69591.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally shortened.The sequence CAA69591.1 differs from that shown. Reason: Frameshift at position 450.
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Research Articles on CHERP

1. analysis of the role of calcium homeostasis endoplasmic reticulum protein (CHERP) in cellular calcium signaling

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CHERP antibody

 Products by Pathway  Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram
 Spliceosome Pathway antibodies  Spliceosome Pathway Diagram

Diseases associated with anti-CHERP antibody

 Disease Name  Pubmed Publications
 Death Antibodies  >2 publications with CHERP and Death
 Breast Neoplasms Antibodies  >1 publications with CHERP and Breast Neoplasms
 Uterine Cervical Neoplasms Antibodies  >1 publications with CHERP and Uterine Cervical Neoplasms
 Precancerous Conditions Antibodies  >1 publications with CHERP and Precancerous Conditions

Organs/Tissues associated with anti-CHERP antibody

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >4 publications with CHERP and Skin
 Heart Antibodies  >2 publications with CHERP and Heart
 Muscle Antibodies  >2 publications with CHERP and Muscle
 Nerve Antibodies  >1 publications with CHERP and Nerve
 Thyroid Antibodies  >1 publications with CHERP and Thyroid
 Prostate Antibodies  >1 publications with CHERP and Prostate
 Eye Antibodies  >1 publications with CHERP and Eye
 Blood Antibodies  >1 publications with CHERP and Blood
 Brain Antibodies  >1 publications with CHERP and Brain
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