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PTPN3 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6495720

MBS6495720 is an antibody targeting PTPN3. Also known as PTPN3 (Protein Tyrosine Phosphatase Non-receptor Type 3, Protein Tyrosine Phosphatase H1, PTP-H1, PTPH1) (APC). Reactive in Human, Mouse. Host: Rabbit. More details

$1060 / 0.2 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PTPN3, Polyclonal Antibody
Full Product Name
PTPN3 (Protein Tyrosine Phosphatase Non-receptor Type 3, Protein Tyrosine Phosphatase H1, PTP-H1, PTPH1) (APC)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein G Affinity Chromatography.
Specificity
Recognizes human PTPN3. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for at least 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
83,723 Da
OMIM
M64572 mRNA
3D Structure
ModBase 3D Structure for P26045
Immunogen
Synthetic peptide selected from the center region of human PTPN3 (KLH).
Conjugate
APC
Note
Preservative Free
Special Handling
Light sensitive

Product Categories/Family for anti-PTPN3 antibody

Applications Tested/Suitable for anti-PTPN3 antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-PTPN3 antibody
IHC: 1:10-1:50
FLISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-PTPN3 antibody

The anti-PTPH1 Center Pab is used in Western blot to detect PTPH1 in mouse brain tissue lysate.
Rabbit Anti-PTPN3 Polyclonal Antibody – Cat# MBS6495720

Immunohistochemistry (IHC) of anti-PTPN3 antibody

Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with PTPH1 antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Rabbit Anti-PTPN3 Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6495720

Product References and Citations for anti-PTPN3 antibody

1. Ikuta, S., et al., J. Gastroenterol. 29(6):727-732 (1994). 2. Arimura, Y., et al., Tumour Biol. 13(3):180-186 (1992). 3. Yang, Q., et al., Proc. Natl. Acad. Sci. USA 88(14):5949-5953 (1991).

Other Notes

Small volumes of anti-PTPN3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTPN3. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tyrosine-protein phosphatase non-receptor type 3 isoform 2
NCBI Official Synonym Full Names
protein tyrosine phosphatase, non-receptor type 3
NCBI Official Symbol
PTPN3
NCBI Official Synonym Symbols
PTPH1; PTP-H1
UniProt Protein Name
Tyrosine-protein phosphatase non-receptor type 3
UniProt Synonym Protein Names
Protein-tyrosine phosphatase H1; PTP-H1
UniProt Gene Name
PTPN3
UniProt Synonym Gene Names
PTPH1; PTP-H1
NCBI Protein Information
tyrosine-protein phosphatase non-receptor type 3

NCBI Summary for PTPN3

The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This protein contains a C-terminal PTP domain and an N-terminal domain homologous to the band 4.1 superfamily of cytoskeletal-associated proteins. P97, a cell cycle regulator involved in a variety of membrane related functions, has been shown to be a substrate of this PTP. This PTP was also found to interact with, and be regulated by adaptor protein 14-3-3 beta. Several alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2009]
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UniProt Comments for PTPN3

May act at junctions between the membrane and the cytoskeleton. Possesses tyrosine phosphatase activity.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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