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Semaphorin 4g (SEMA4G) Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649637

MBS649637 is an antibody targeting SEMA4G. Also known as Semaphorin 4G (Semaphorin-4G, SEMA4G, KIAA1619). Reactive in Human. Host: Mouse. More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Semaphorin 4G (SEMA4G), Monoclonal Antibody
Full Product Name
Semaphorin 4G (Semaphorin-4G, SEMA4G, KIAA1619)
Product Gene Name
Product Synonym Names
Anti -Semaphorin 4G (Semaphorin-4G, SEMA4G, KIAA1619)
Immunogen Sequence
RRPSRELDAT PRMTIPYEEL SGTRHFKGQA QNYSTLLLEE ASARLLVGAR GALFSLSAND IGDGAHKEIH WEASPEMQSK CHQKGKNNQT EC
Clonality
Monoclonal
Isotype
IgG2a,k
Clone Number
3F2
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human SEMA4G.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
91,497 Da
Chromosome Location
Chromosome: 10; NC_000010.10 (102729254..102745373). Location: 10q24.31
3D Structure
ModBase 3D Structure for Q9NTN9
Immunogen
Partial recombinant corresponding to aa24-116 from human SEMA4G (NP_060363) with GST tag. MW of the GST tag alone is 26kD.
Applications Tested/Suitable for anti-SEMA4G antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-SEMA4G antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-SEMA4G antibody

Western Blot detection against Immunogen (36.23kD).
Mouse Anti-SEMA4G Monoclonal Antibody – Cat# MBS649637

Other Notes

Small volumes of anti-SEMA4G antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SEMA4G. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
semaphorin-4G isoform 1
NCBI Official Synonym Full Names
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4G
NCBI Official Symbol
SEMA4G
UniProt Protein Name
Semaphorin-4G
Protein Family
UniProt Gene Name
SEMA4G
UniProt Synonym Gene Names
KIAA1619
UniProt Entry Name
SEM4G_HUMAN
NCBI Protein Information
semaphorin-4G

NCBI Summary for SEMA4G

Semaphorins are a large family of conserved secreted and membrane associated proteins which possess a semaphorin (Sema) domain and a PSI domain (found in plexins, semaphorins and integrins) in the N-terminal extracellular portion. Based on sequence and structural similarities, semaphorins are put into eight classes: invertebrates contain classes 1 and 2, viruses have class V, and vertebrates contain classes 3-7. Semaphorins serve as axon guidance ligands via multimeric receptor complexes, some (if not all) containing plexin proteins. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
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UniProt Comments for SEMA4G

Function: Cell surface receptor for PLXNB2. May play a role in axon guidance

By similarity.

Subunit structure: Interacts with PLXNB2

By similarity.

Subcellular location: Cell membrane; Single-pass type I membrane protein.

Sequence similarities: Belongs to the semaphorin family.Contains 1 Ig-like C2-type (immunoglobulin-like) domain.Contains 1 PSI domain.Contains 1 Sema domain.

Sequence caution: The sequence BAB13445.1 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-SEMA4G antibody

Organs/Tissues associated with anti-SEMA4G antibody

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