Rabbit Anti-TBC1D10B Polyclonal Antibody – Cat# MBS649752

TBC1D10B Antibody (C-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the TBC1D10B antibody detected the TBC1D10B protein (arrow).

TBC1D10B Antibody – Rabbit Polyclonal

Name: TBC1D10B Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS649752
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649752

Small G proteins of the RAB family (see MIM 179508) function in intracellular vesicle trafficking by switching from the GTP-bound state to the GDP-bound state with the assistance of guanine nucleotide exchange factors (GEFs; see MIM 609700) and… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TBC1D10B, Polyclonal Antibody

Full Product Name

TBC1D10B, CT (TBC1D10B, TBC1 domain family member 10B, Rab27A-GAP-beta)

Product Gene Name

anti-TBC1D10B antibody

Product Synonym Names

Anti -TBC1D10B, CT (TBC1D10B, TBC1 domain family member 10B, Rab27A-GAP-beta)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

87,199 Da

Chromosome Location

Chromosome: 16; NC_000016.9 (30368422..30381522, complement). Location: 16p11.2

OMIM

613620

3D Structure

ModBase 3D Structure for Q4KMP7

Immunogen

TBC1D10B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 780-808 amino acids from the C-terminal region of human TBC1D10B.

Product Categories/Family for anti-TBC1D10B antibody

Antibodies; Abs to GTPase; Rab; Ras; Rho Proteins

Applications Tested/Suitable for anti-TBC1D10B antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-TBC1D10B antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-TBC1D10B antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TBC1D10B purchase

MBS649752 is an antibody targeting TBC1D10B. Also known as TBC1D10B, CT (TBC1D10B, TBC1 domain family member 10B, Rab27A-GAP-beta). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TBC1D10B. It may not necessarily be applicable to this product.

NCBI GI #

167614488

NCBI GeneID

26000

NCBI Accession #

NP_056342.3

UniProt Primary Accession #

Q4KMP7

UniProt Secondary Accession #

Q6IN54; Q6P530; Q71RG7; Q86VC5; Q9H8Z2; Q9NUN6; Q9UFP2; B9A6L0

UniProt Related Accession #

Q4KMP7

GenBank Nucleotide #

NM_015527.3

NCBI Official Full Name

TBC1 domain family member 10B

NCBI Official Synonym Full Names

TBC1 domain family, member 10B

NCBI Official Symbol

TBC1D10B

NCBI Official Synonym Symbols

EPI64B; FP2461

UniProt Protein Name

TBC1 domain family member 10B

UniProt Synonym Protein Names

Rab27A-GAP-beta

Protein Family

TBC1 domain family

UniProt Gene Name

TBC1D10B

UniProt Entry Name

TB10B_HUMAN

NCBI Protein Information

TBC1 domain family member 10B; Rab27A-GAPbeta; rab27A-GAP-beta

UniProt Comments for TBC1D10B

Function: Acts as GTPase-activating protein for RAB3A, RAB22A, RAB27A, AND RAB35. Does not act on RAB2A and RAB6A. Ref.6 Ref.9

Subcellular location: Cytoplasm. Note: In melanocytes, located at the periphery of cells. Ref.9

Sequence similarities: Contains 1 Rab-GAP TBC domain.

Sequence caution: The sequence AAH50523.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH63112.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH72453.2 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH93814.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH93816.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAH98419.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence AAQ15206.1 differs from that shown. Reason: Frameshift at positions 154, 379 and 401. The sequence BAA92086.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence BAB14454.1 differs from that shown. Reason: Erroneous initiation. Translation N-terminally extended.The sequence BAH16638.1 differs from that shown. Reason: Probable cloning artifact.The sequence EAW52256.1 differs from that shown. Reason: Erroneous gene model prediction.

Research Articles on TBC1D10B

1. Data suggest that EPI64A and B, which are ubiquitously expressed members of the EPI64 subfamily, inactivate Ras and certain Rabs at the periphery of cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-TBC1D10B antibody

Reference Product	PubMed Publications
CDC16 antibody	>1 publications with TBC1D10B and CDC16
RAB35 antibody	>1 publications with TBC1D10B and RAB35
RAB27A antibody	>1 publications with TBC1D10B and RAB27A

Organs/Tissues associated with anti-TBC1D10B antibody

Organ/Tissue Name	Pubmed Publications
Pancreas Antibodies	>1 publications with TBC1D10B and Pancreas