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NLGN4Y Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649831

Neuroligins, such as NLGN4Y, are cell adhesion molecules present at the postsynaptic side of the synapse and may be essential for the formation of functional synapses (Jamain et al., 2003 [PubMed 12669065]). More details

$880 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NLGN4Y, Monoclonal Antibody
Full Product Name
NLGN4Y (KIAA0951, Neuroligin-4, Y-linked)
Product Gene Name
Product Synonym Names
Anti -NLGN4Y (KIAA0951, Neuroligin-4, Y-linked)
Immunogen Sequence
MLPIWFTTSL DTLMTYVQDQ NEDCLYLNIY VPMEDGTNIK RNADDITSND HGEDKDIHEQ NSKKPVMVYI HGGSYMEGTG NMIDGSILAS YGNVIVITIN YRLGILGMQE ARLCGSSKMF NYFKSPFTNL INFF*
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
1E4
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human NLGN4Y.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
92,021 Da
Chromosome Location
Chromosome: Y; NC_000024.9 (16634488..16956825). Location: Yq11.221
OMIM
400028
3D Structure
ModBase 3D Structure for Q8NFZ3
Immunogen
Full length recombinant corresponding to aa1-135 from NLGN4Y (AAH32567) with GST tag. MW of the GST tag alone is 26kD.

Product Categories/Family for anti-NLGN4Y antibody

Applications Tested/Suitable for anti-NLGN4Y antibody
ELISA (EL/EIA), Western Blot (WB)
Application Notes for anti-NLGN4Y antibody
Suitable for use in ELISA and Western Blot.

Western Blot (WB) of anti-NLGN4Y antibody

Western Blot detection against Immunogen (40.85kD).
Mouse Anti-NLGN4Y Monoclonal Antibody – Cat# MBS649831

Testing Data of anti-NLGN4Y antibody

Detection limit for recombinant GST tagged NLGN4Y is ~0.1ng/ml as a capture antibody.
Mouse Anti-NLGN4Y Monoclonal Antibody, Testing Data – Cat# MBS649831

Other Notes

Small volumes of anti-NLGN4Y antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for NLGN4Y purchase

MBS649831 is an antibody targeting NLGN4Y. Also known as NLGN4Y (KIAA0951, Neuroligin-4, Y-linked). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for NLGN4Y. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
neuroligin-4, Y-linked isoform 3
NCBI Official Synonym Full Names
neuroligin 4, Y-linked
NCBI Official Symbol
NLGN4Y
UniProt Protein Name
Neuroligin-4, Y-linked
Protein Family
UniProt Gene Name
NLGN4Y
UniProt Synonym Gene Names
KIAA0951; Neuroligin Y
UniProt Entry Name
NLGNY_HUMAN
NCBI Protein Information
neuroligin-4, Y-linked

NCBI Summary for NLGN4Y

This gene encodes a type I membrane protein that belongs to the family of neuroligins, which are cell adhesion molecules present at the postsynaptic side of the synapse, and may be essential for the formation of functional synapses. Alternatively spliced transcript variants have been found for this gene.[provided by RefSeq, Mar 2011]
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UniProt Comments for NLGN4Y

Function: Putative neuronal cell surface protein involved in cell-cell-interactions.

Subunit structure: Homodimer. Interacts with NRXN1 in a calcium-dependent manner. Interacts through its C-terminus with DLG4/PSD-95 third PDZ domain

By similarity.

Subcellular location: Cell membrane; Single-pass type I membrane protein. Cell junction › synapse › postsynaptic cell membrane › postsynaptic density

By similarity.

Tissue specificity: Expressed in fetal and adult brain, prostate and testis. Ref.4

Sequence similarities: Belongs to the type-B carboxylesterase/lipase family.

Sequence caution: The sequence BAA76795.2 differs from that shown. Reason: Erroneous initiation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.
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