Goat Anti-RBM20 Polyclonal Antibody – Cat# MBS649901

(1ug/ml) staining of Mouse Heart lysate (35ug protein in RIPA buffer) with (B) and without (A) blocking with the immunising peptide. Primary incubation was 1 hour. Detected by chemiluminescence.

RBM20 Antibody – Goat Polyclonal

Name: RBM20 Antibody; Polyclonal; Goat; MyBioSource
Brand: MyBioSource
SKU: MBS649901
Price: 835 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649901

MBS649901 is an antibody targeting RBM20. Also known as RBM20 (Probable RNA-binding Protein 20, RNA-binding Motif Protein 20). Reactive in Bovine, Human, Mouse, Rat. Host: Goat. Expressed in the heart. More details

$835 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

RBM20, Polyclonal Antibody

Full Product Name

RBM20 (Probable RNA-binding Protein 20, RNA-binding Motif Protein 20)

Product Gene Name

anti-RBM20 antibody

Product Synonym Names

Anti -RBM20 (Probable RNA-binding Protein 20, RNA-binding Motif Protein 20)

Clonality

Polyclonal

Host

Goat

Species Reactivity

Bovine, Human, Mouse, Rat

Form/Format

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

Purity/Purification

Affinity Purified
Purified by immunoaffinity chromatography.

Specificity

Recognizes mouse RBM20. Species sequence homology: Bovine, human and rat.

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

134,357 Da

Chromosome Location

Chromosome: 10; NC_000010.10 (112404155..112599227). Location: 10q25.2

OMIM

613171

3D Structure

ModBase 3D Structure for Q5T481

Immunogen

Synthetic peptide corresponding to C-QLDKAELDERP, from mouse RBM20, at the internal region of the protein (NP_001127835.1).

Product Categories/Family for anti-RBM20 antibody

Antibodies; Abs to Binding Proteins

Applications Tested/Suitable for anti-RBM20 antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-RBM20 antibody

Suitable for use in ELISA and Western Blot.
Dilution: ELISA: 1:8000
Western Blot: 1-3ug/ml, mouse heart lysates observed on ~150kD bands

Other Notes

Small volumes of anti-RBM20 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for RBM20. It may not necessarily be applicable to this product.

NCBI GI #

197276594

NCBI GeneID

282996

NCBI Accession #

NP_001127835.1

UniProt Primary Accession #

Q5T481

UniProt Secondary Accession #

Q5JVI1; A6NIP5; B5A868

UniProt Related Accession #

Q5T481

GenBank Nucleotide #

NM_001134363.1

NCBI Official Full Name

RNA-binding protein 20

NCBI Official Synonym Full Names

RNA binding motif protein 20

NCBI Official Symbol

RBM20

UniProt Protein Name

RNA-binding protein 20

UniProt Synonym Protein Names

RNA-binding motif protein 20

Protein Family

RNA-binding protein

UniProt Gene Name

RBM20

UniProt Entry Name

RBM20_HUMAN

NCBI Protein Information

RNA-binding protein 20; RNA-binding motif protein 20; probable RNA-binding protein 20

NCBI Summary for RBM20

This gene encodes a protein that likely binds RNA. Mutations in this gene have been associated with familial dilated cardiomyopathy. [provided by RefSeq, Mar 2010]

UniProt Comments for RBM20

Function: RNA-binding protein that acts as a regulator of mRNA splicing of a subset of genes involved in cardiac development. Regulates splicing of TTN (Titin). Ref.1

Subcellular location: Nucleus

By similarity.

Tissue specificity: Expressed in the heart. Ref.3

Involvement in disease: Cardiomyopathy, dilated 1DD (CMD1DD) [MIM:613172]: A disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Patients are at risk of premature death.Note: The disease is caused by mutations affecting the gene represented in this entry. Ref.1 Ref.3 Ref.4 Ref.5

Sequence similarities: Contains 1 RRM (RNA recognition motif) domain.

Sequence caution: The sequence CAI16577.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI40091.1 differs from that shown. Reason: Erroneous gene model prediction. The sequence CAI40093.1 differs from that shown. Reason: Erroneous gene model prediction.

Research Articles on RBM20

1. Mutations in RBM20 identified in approximately 3% of individuals with dilated cardiomyopathy. Mutations in RBM20 did not adversely affect survival or ventricular arrhythmias in subjects with dilated cardiomyopathy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-RBM20 antibody

Reference Product	PubMed Publications
MYBPC3 antibody	>1 publications with RBM20 and MYBPC3
CSRP3 antibody	>1 publications with RBM20 and CSRP3
TNNC1 antibody	>1 publications with RBM20 and TNNC1

Diseases associated with anti-RBM20 antibody

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>7 publications with RBM20 and Cardiovascular Diseases

Organs/Tissues associated with anti-RBM20 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>5 publications with RBM20 and Muscle