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PRRX2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649906

MBS649906 is an antibody targeting PRRX2. Also known as PRRX2 (Paired Mesoderm Homeobox Protein 2, Paired-related Homeobox Protein 2, PMX2, PRX2, PRX-2). Reactive in Human, Mouse. Host: Rabbit. More details

$970 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
PRRX2, Polyclonal Antibody
Full Product Name
PRRX2 (Paired Mesoderm Homeobox Protein 2, Paired-related Homeobox Protein 2, PMX2, PRX2, PRX-2)
Product Gene Name
Product Synonym Names
Anti -PRRX2 (Paired Mesoderm Homeobox Protein 2, Paired-related Homeobox Protein 2, PMX2, PRX2, PRX-2)
Immunogen Sequence
MDSAAAAFAL DKPALGPGPP PPPPALGPGD CAQARKNFSV SHLLDLEEVA AAGRLAARPG ARAEAREGAA REPSGGSSGS EAAPQDGECP SPGRGSAAKR KKKQRRNRTT FNSSQLQALE RVFERTHYPD AFVREELARR VNLSEARVQV WFQNRRAKFR RNERAMLASR SASLLKSYSQ EAAIEQPVAP RPTALSPDYL SWTASSPYST VPPYSPGSSG PATPGVNMAN SIASLRLKAK EFSLHHSQVP TVN
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid.
Purity/Purification
Serum
Serum
Specificity
Recognizes human PRRX2. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
27,079 Da
Chromosome Location
Chromosome: 9; NC_000009.11 (132427920..132484953). Location: 9q34.1
OMIM
604675
3D Structure
ModBase 3D Structure for Q99811
Immunogen
Full length human PRRX2, aa1-253 (NP_057391.1).
Applications Tested/Suitable for anti-PRRX2 antibody
Western Blot (WB), Immunoprecipitation (IP)
Application Notes for anti-PRRX2 antibody
Suitable for use in Western Blot and Immunoprecipitation.

Western Blot (WB) of anti-PRRX2 antibody

PRRX2 rabbit polyclonal antibody. Western Blot analysis of PRRX2 expression in mouse brain.
Rabbit Anti-PRRX2 Polyclonal Antibody – Cat# MBS649906

Western Blot (WB) of anti-PRRX2 antibody

Western Blot analysis of PRRX2 expression in transfected 293T cell line by PRRX2 polyclonal antibody. Lane 1: PRRX2 transfected lysate (27.1kD). Lane 2: Non-transfected lysate.
Rabbit Anti-PRRX2 Polyclonal Antibody, Western Blot (WB) – Cat# MBS649906

Immunoprecipitation (IP) of anti-PRRX2 antibody

Immunoprecipitation of PRRX2 transfected lysate using PRRX2 rabbit polyclonal antibody and Protein A Magnetic Bead and immunoblotted with PRRX2 mouse polyclonal antibody.
Rabbit Anti-PRRX2 Polyclonal Antibody, Immunoprecipitation (IP) – Cat# MBS649906

Other Notes

Small volumes of anti-PRRX2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PRRX2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
paired mesoderm homeobox protein 2
NCBI Official Synonym Full Names
paired related homeobox 2
NCBI Official Symbol
PRRX2
NCBI Official Synonym Symbols
PMX2; PRX2
UniProt Protein Name
Paired mesoderm homeobox protein 2
UniProt Synonym Protein Names
Paired-related homeobox protein 2
UniProt Gene Name
PRRX2
UniProt Synonym Gene Names
PMX2; PRX2; PRX-2
UniProt Entry Name
PRRX2_HUMAN
NCBI Protein Information
paired mesoderm homeobox protein 2; PRX-2; paired-related homeobox protein 2; paired-like homeodomain protein PRX2

NCBI Summary for PRRX2

The DNA-associated protein encoded by this gene is a member of the paired family of homeobox proteins. Expression is localized to proliferating fetal fibroblasts and the developing dermal layer, with downregulated expression in adult skin. Increases in expression of this gene during fetal but not adult wound healing suggest a possible role in mechanisms that control mammalian dermal regeneration and prevent formation of scar response to wounding. The expression patterns provide evidence consistent with a role in fetal skin development and a possible role in cellular proliferation. [provided by RefSeq, Jul 2008]
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UniProt Comments for PRRX2

Function: May play a role in the scarless healing of cutaneous wounds during the first two trimesters of development. Ref.5

Subcellular location: Nucleus

By similarity.

Tissue specificity: In fetal skin, highest expression found in cells of mesodermal origin within the dermal papilla of the developing hair shaft. Not detected in epidermis or dermis. In adult skin, weakly expressed within the basal layers of the epidermis. Not expressed in dermis. Ref.5

Developmental stage: Higher expression in fetus than in adult. Ref.5

Sequence similarities: Belongs to the paired homeobox family.Contains 1 homeobox DNA-binding domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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