Rabbit Anti-HSPA1L Polyclonal Antibody – Cat# MBS649913

HSPA1L Antibody (C-term) western blot analysis in MDA-MB453 cell line lysates (35ug/lane).This demonstrates the HSPA1L antibody detected the HSPA1L protein (arrow).

HSPA1L Antibody – Rabbit Polyclonal

Name: HSPA1L Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS649913
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649913

In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through… More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

HSPA1L, Polyclonal Antibody

Full Product Name

HSPA1L, CT (Heat shock 70kD protein 1-like,)

Product Gene Name

anti-HSPA1L antibody

Product Synonym Names

Anti -HSPA1L, CT (Heat shock 70kD protein 1-like,)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

70,375 Da

Chromosome Location

Chromosome: 6; NC_000006.11 (31777396..31790093, complement). Location: 6p21.3

OMIM

140559

3D Structure

ModBase 3D Structure for P34931

Immunogen

HSPA1L antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 576-603 amino acids from the C-terminal region of human HSPA1L.

Product Categories/Family for anti-HSPA1L antibody

Antibodies; Abs to Heat Shock Proteins

Applications Tested/Suitable for anti-HSPA1L antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-HSPA1L antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-HSPA1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for HSPA1L purchase

MBS649913 is an antibody targeting HSPA1L. Also known as HSPA1L, CT (Heat shock 70kD protein 1-like,). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for HSPA1L. It may not necessarily be applicable to this product.

NCBI GI #

124256496

NCBI GeneID

3305

NCBI Accession #

NP_005518.3

UniProt Primary Accession #

P34931

UniProt Secondary Accession #

O75634; Q2HXR3; Q8NE72; Q96QC9; Q9UQM1; A6NNB0; B0UXW8

UniProt Related Accession #

P34931

GenBank Nucleotide #

NM_005527.3

NCBI Official Full Name

heat shock 70 kDa protein 1-like

NCBI Official Synonym Full Names

heat shock 70kDa protein 1-like

NCBI Official Symbol

HSPA1L

NCBI Official Synonym Symbols

HSP70T; hum70t; HSP70-1L; HSP70-HOM

UniProt Protein Name

Heat shock 70 kDa protein 1-like

UniProt Synonym Protein Names

Heat shock 70 kDa protein 1-Hom

Protein Family

Heat shock 70 kDa protein

UniProt Gene Name

HSPA1L

UniProt Synonym Gene Names

Heat shock 70 kDa protein 1L; HSP70-Hom

UniProt Entry Name

HS71L_HUMAN

NCBI Protein Information

heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 1L; heat shock 70kD protein-like 1; heat shock 10kDa protein 1-like; heat shock 70 kDa protein 1-Hom

NCBI Summary for HSPA1L

This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008]

UniProt Comments for HSPA1L

Function: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage

By similarity.

Tissue specificity: Expressed in spermatids. Ref.2

Induction: Not induced by heat shock. Ref.1

Sequence similarities: Belongs to the heat shock protein 70 family.

Research Articles on HSPA1L

1. The risk for the development of chronic hepatitis and hepatocellular carcinoma compared to healthy controls irrespective of the aetiology was significant in terms of the HSPA1B marker than HSPA1L in the Indian population.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-HSPA1L antibody

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Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Estrogen Signaling Pathway antibodies	Estrogen Signaling Pathway Diagram
Estrogen Signaling Pathway antibodies	Estrogen Signaling Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram
Influenza A Pathway antibodies	Influenza A Pathway Diagram

Diseases associated with anti-HSPA1L antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with HSPA1L and Neoplasms
Cardiovascular Diseases Antibodies	>5 publications with HSPA1L and Cardiovascular Diseases
Necrosis Antibodies	>4 publications with HSPA1L and Necrosis
Inflammation Antibodies	>3 publications with HSPA1L and Inflammation
Lung Diseases Antibodies	>3 publications with HSPA1L and Lung Diseases
Drug Hypersensitivity Antibodies	>3 publications with HSPA1L and Drug Hypersensitivity
Carcinoma, Hepatocellular Antibodies	>2 publications with HSPA1L and Carcinoma, Hepatocellular
Liver Neoplasms Antibodies	>2 publications with HSPA1L and Liver Neoplasms
Liver Diseases Antibodies	>2 publications with HSPA1L and Liver Diseases
Heart Diseases Antibodies	>2 publications with HSPA1L and Heart Diseases

Organs/Tissues associated with anti-HSPA1L antibody

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>2 publications with HSPA1L and Testis
Kidney Antibodies	>1 publications with HSPA1L and Kidney
Lung Antibodies	>1 publications with HSPA1L and Lung
Eye Antibodies	>1 publications with HSPA1L and Eye
Connective Tissue Antibodies	>1 publications with HSPA1L and Connective Tissue