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CLTB Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649946

Clathrin is the major protein of the polyhedral coat of coated pits and vesicles. More details

$970 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CLTB, Polyclonal Antibody
Full Product Name
CLTB (Clathrin Light Chain B, Lcb)
Product Gene Name
Product Synonym Names
Anti -CLTB (Clathrin Light Chain B, Lcb)
Immunogen Sequence
MADDFGFFSS SESGAPEAAE EDPAAAFLAQ QESEIAGIEN DEGFGAPAGS HAAPAQPGPT SGAGSEDMGT TVNGDVFQEA NGPADGYAAI AQADRLTQEP ESIRKWREEQ RKRLQELDAA SKVTEQEWRE KAKKDLEEWN QRQSEQVEKN KINNRASEEA FVKESKEETP GTEWEKVAQL CDFNPKSSKQ CKDVSRLRSV LMSLKQTPLS R
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human, Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2.
Purity/Purification
Affinity Purified
Purified by Protein A affinity chromatography.
Specificity
Recognizes human CLTB. Species Crossreactivity: mouse.
Preparation and Storage
May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
25,190 Da
Chromosome Location
Chromosome: 5; NC_000005.9 (175819456..175843570, complement). Location: 5q35
OMIM
118970
3D Structure
ModBase 3D Structure for P09497
Immunogen
Full length human CLTB, aa1-211 (NP_001825.1).

Product Categories/Family for anti-CLTB antibody

Applications Tested/Suitable for anti-CLTB antibody
Western Blot (WB)
Application Notes for anti-CLTB antibody
Suitable for use in Western Blot.

Western Blot (WB) of anti-CLTB antibody

CLTB rabbit polyclonal antibody. Western Blot analysis of CLTB expression in human stomach.
Rabbit Anti-CLTB Polyclonal Antibody – Cat# MBS649946

Western Blot (WB) of anti-CLTB antibody

CLTB rabbit polyclonal antibody. Western Blot analysis of CLTB expression in mouse spleen.
Rabbit Anti-CLTB Polyclonal Antibody, Western Blot (WB) – Cat# MBS649946

Western Blot (WB) of anti-CLTB antibody

Western Blot analysis of CLTB expression in transfected 293T cell line by CLTB rabbit polyclonal antibody. Lane 1: CLTB transfected lysate (23.2kD). Lane 2: Non-transfected lysate.
Rabbit Anti-CLTB Polyclonal Antibody, Western Blot (WB) – Cat# MBS649946

Other Notes

Small volumes of anti-CLTB antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CLTB purchase

MBS649946 is an antibody targeting CLTB. Also known as CLTB (Clathrin Light Chain B, Lcb). Reactive in Human, Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for CLTB. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
clathrin light chain B isoform b
NCBI Official Synonym Full Names
clathrin, light chain B
NCBI Official Symbol
CLTB
NCBI Official Synonym Symbols
LCB
UniProt Protein Name
Clathrin light chain B
Protein Family
UniProt Gene Name
CLTB
UniProt Synonym Gene Names
Lcb
UniProt Entry Name
CLCB_HUMAN
NCBI Protein Information
clathrin light chain B; clathrin, light chain (Lcb); clathrin, light polypeptide (Lcb)

NCBI Summary for CLTB

Clathrin is a large, soluble protein composed of heavy and light chains. It functions as the main structural component of the lattice-type cytoplasmic face of coated pits and vesicles which entrap specific macromolecules during receptor-mediated endocytosis. This gene encodes one of two clathrin light chain proteins which are believed to function as regulatory elements. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2008]
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UniProt Comments for CLTB

Function: Clathrin is the major protein of the polyhedral coat of coated pits and vesicles.

Subunit structure: Clathrin coats are formed from molecules containing 3 heavy chains and 3 light chains. Interacts (via N-terminus) with HIP1. Interacts with HIP1R. Ref.6 Ref.7

Subcellular location: Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Membrane › coated pit; Peripheral membrane protein; Cytoplasmic side. Note: Cytoplasmic face of coated pits and vesicles.

Sequence similarities: Belongs to the clathrin light chain family.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-CLTB antibody

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