Rabbit Anti-TMPRSS11E Polyclonal Antibody – Cat# MBS649989

TMPRSS11E2 Antibody (Center) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the TMPRSS11E2 antibody detected the TMPRSS11E2 protein (arrow).

Tmprss11e2 (TMPRSS11E) Antibody – Rabbit Polyclonal

Name: TMPRSS11E Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS649989
Price: 895 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS649989

TMPRSS11E is a serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position (By similarity). More details

$895 / 0.2 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

TMPRSS11E2, Polyclonal Antibody

Full Product Name

TMPRSS11E2, ID (TMPRSS11E, DESC1, TMPRSS11E2, Transmembrane protease serine 11E, Serine protease DESC1, Transmembrane protease serine 11E2, Transmembrane protease serine 11E non-catalytic chain, Transmembrane protease serine 11E catalytic chain)

Product Gene Name

anti-TMPRSS11E antibody

Product Synonym Names

Anti -TMPRSS11E2, ID (TMPRSS11E, DESC1, TMPRSS11E2, Transmembrane protease serine 11E, Serine protease DESC1, Transmembrane protease serine 11E2, Transmembrane protease serine 11E non-catalytic chain, Transmembrane protease serine 11E catalytic chain)

Clonality

Polyclonal

Isotype

IgG

Host

Rabbit

Species Reactivity

Human

Form/Format

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Purity/Purification

Affinity Purified
Purified by Protein A affinity chromatography.

Specificity

Human

Preparation and Storage

May be stored at 4 degree C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Molecular Weight

47,696 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (69313167..69363322). Location: 4q13.2

OMIM

610399

3D Structure

ModBase 3D Structure for Q9UL52

Immunogen

TMPRSS11E2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 amino acids from the Central region of human TMPRSS11E2.

Product Categories/Family for anti-TMPRSS11E antibody

Antibodies; Abs to Transmembrane Proteins

Applications Tested/Suitable for anti-TMPRSS11E antibody

ELISA (EL/EIA), Western Blot (WB)

Application Notes for anti-TMPRSS11E antibody

Suitable for use in Western Blot, ELISA
Dilution: ELISA: 1:1,000
Western Blot: 1:100-500

Other Notes

Small volumes of anti-TMPRSS11E antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TMPRSS11E purchase

MBS649989 is an antibody targeting TMPRSS11E. Also known as TMPRSS11E2, ID (TMPRSS11E, DESC1, TMPRSS11E2, Transmembrane protease serine 11E, Serine protease DESC1, Transmembrane protease serine 11E2, Transmembrane protease serine 11E non-catalytic chain, Transmembrane protease serine 11E catalytic chain). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for TMPRSS11E. It may not necessarily be applicable to this product.

NCBI GI #

40254871

NCBI GeneID

28983

NCBI Accession #

NP_054777.2

UniProt Primary Accession #

Q9UL52

UniProt Secondary Accession #

Q14DC8; Q6UW31; A6NL71

UniProt Related Accession #

Q9UL52

GenBank Nucleotide #

NM_014058.3

NCBI Official Full Name

transmembrane protease serine 11E

NCBI Official Synonym Full Names

transmembrane protease, serine 11E

NCBI Official Symbol

TMPRSS11E

NCBI Official Synonym Symbols

DESC1; TMPRSS11E2

UniProt Protein Name

Transmembrane protease serine 11E

UniProt Synonym Protein Names

Serine protease DESC1; Transmembrane protease serine 11E2

Protein Family

Transmembrane protease serine

UniProt Gene Name

TMPRSS11E

UniProt Synonym Gene Names

DESC1; TMPRSS11E2

UniProt Entry Name

TM11E_HUMAN

NCBI Protein Information

transmembrane protease serine 11E; serine protease DESC1; transmembrane protease serine 11E2; transmembrane protease, serine 11E2

UniProt Comments for TMPRSS11E

Function: Serine protease which possesses both gelatinolytic and caseinolytic activities. Shows a preference for Arg in the P1 position

By similarity.

Enzyme regulation: Inhibited by SERPINA5. Ref.5

Subunit structure: Forms a heterodimer with SERPINA5 and SERPINE1.

Subcellular location: Cell membrane; Single-pass type II membrane protein

By similarity. Transmembrane protease serine 11E catalytic chain: Secreted

By similarity. Note: Activated by cleavage and secreted

By similarity.

Tissue specificity: Expression can only be detected in tissues derived from the head and neck, and in skin, prostate and testis. Ref.1

Post-translational modification: N-glycosylated

By similarity.

Sequence similarities: Belongs to the peptidase S1 family.Contains 1 peptidase S1 domain.Contains 1 SEA domain.

Caution: It is uncertain whether Met-1 or Met-2 is the initiator.

Research Articles on TMPRSS11E

1. The domain of DESC1 exhibits a trypsin-like serine proteinase fold with a thrombin-like S1 pocket, a urokinase-type plasminogen activator-type S2 pocket, to accept small residues, and an open hydrophobic S3/S4 cavity to accept large hydrophobic residues.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.