Epidermal Growth Factor (EGF) Active Protein

Name: EGF Active Protein; Epidermal Growth Factor; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS650102
Price: 500 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650102

Human EGF is produced by genetically engineered yeast, and purified by sequential chromatography and reverse-phase HPLC. This polypeptide is identical to gamma-urogastrone, or equivalent to human. More details

$500 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Epidermal Growth Factor (EGF), Active Protein

Full Product Name

Epidermal Growth Factor, Recombinant, Human (EGF, beta-Urogastrone, URG)

Product Gene Name

EGF active protein

Host

EGF1-52

Form/Format

Supplied as a lyophilized powder in PBS

Purity/Purification

Purified
Purified. 97% pure by N-terminal aa sequencing, aa composition, HPLC analysis, and SDS gel electrophoresis

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Reconstitute to with sterile dH2O or buffer, aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

6,222 Da

Chromosome Location

Chromosome: 4; NC_000004.11 (110834040..110934118). Location: 4q25

3D Structure

ModBase 3D Structure for Q6QBS2

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

The mitogenic activity of human EGF is measured by the stimulation of 3H-thymidine incorporation into human foreskin fibroblast cells. In addition, EGF activity has been determined by a receptor-binding assay (RBA) using A-431 cells.

Product Categories/Family for EGF active protein

Growth Factors; Cytokines; Growth Factors-EGF

Other Notes

Small volumes of EGF active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EGF purchase

MBS650102 is an active protein targeting EGF. Also known as Epidermal Growth Factor, Recombinant, Human (EGF, beta-Urogastrone, URG). Host: EGF1-52.

Additional Details

NCBI/Uniprot data below describe general gene information for EGF. It may not necessarily be applicable to this product.

NCBI GI #

46242544

NCBI GeneID

1950

UniProt Primary Accession #

Q6QBS2

UniProt Related Accession #

P01133; Q6QBS2

NCBI Official Full Name

epidermal growth factor

NCBI Official Synonym Full Names

epidermal growth factor

NCBI Official Symbol

EGF

NCBI Official Synonym Symbols

URG; HOMG4

UniProt Protein Name

Epidermal growth factor

Protein Family

Pro-epidermal growth factor

UniProt Gene Name

EGF

UniProt Entry Name

Q6QBS2_HUMAN

NCBI Protein Information

pro-epidermal growth factor; beta-urogastrone; OTTHUMP00000162922; OTTHUMP00000219721; OTTHUMP00000219722

NCBI Summary for EGF

This gene encodes a member of the epidermal growth factor superfamily. The encoded protein is synthesized as a large precursor molecule that is proteolytically cleaved to generate the 53-amino acid epidermal growth factor peptide. This protein acts a potent mitogenic factor that plays an important role in the growth, proliferation and differentiation of numerous cell types. This protein acts by binding the high affinity cell surface receptor, epidermal growth factor receptor. Defects in this gene are the cause of hypomagnesemia type 4. Dysregulation of this gene has been associated with the growth and progression of certain cancers. Alternate splicing results in multiple transcript variants.

Research Articles on EGF

1. Data show that males, but not females, who are A carriers for EGF +61 have an increased risk for developing gastric cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with EGF active protein

Reference Product	PubMed Publications
EGFR active protein	>4126 publications with EGF and EGFR
ERBB2 active protein	>1134 publications with EGF and ERBB2
GRB2 active protein	>325 publications with EGF and GRB2
ERBB3 active protein	>217 publications with EGF and ERBB3

Pathways associated with EGF active protein

Products by Pathway	Pathway Diagram
Arf6 Signaling Events Pathway antibodies	Arf6 Signaling Events Pathway Diagram
Bladder Cancer Pathway antibodies	Bladder Cancer Pathway Diagram
Bladder Cancer Pathway antibodies	Bladder Cancer Pathway Diagram
Ceramide Signaling Pathway antibodies	Ceramide Signaling Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Delta-Notch Signaling Pathway antibodies	Delta-Notch Signaling Pathway Diagram
EGF Receptor (ErbB1) Signaling Pathway antibodies	EGF Receptor (ErbB1) Signaling Pathway Diagram
EGFR Downregulation Pathway antibodies	EGFR Downregulation Pathway Diagram
EGFR Interacts With Phospholipase C-gamma Pathway antibodies	EGFR Interacts With Phospholipase C-gamma Pathway Diagram

Diseases associated with EGF active protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>6899 publications with EGF and Neoplasms
Breast Neoplasms Antibodies	>1366 publications with EGF and Breast Neoplasms
Adenocarcinoma Antibodies	>1086 publications with EGF and Adenocarcinoma
Carcinoma, Squamous Cell Antibodies	>1034 publications with EGF and Carcinoma, Squamous Cell
Cell Transformation, Neoplastic Antibodies	>777 publications with EGF and Cell Transformation, Neoplastic
Neoplasms, Experimental Antibodies	>716 publications with EGF and Neoplasms, Experimental
Lung Neoplasms Antibodies	>580 publications with EGF and Lung Neoplasms
Drug Toxicity Antibodies	>560 publications with EGF and Drug Toxicity
Head and Neck Neoplasms Antibodies	>546 publications with EGF and Head and Neck Neoplasms
Neoplasm Metastasis Antibodies	>455 publications with EGF and Neoplasm Metastasis

Organs/Tissues associated with EGF active protein

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>1523 publications with EGF and Brain
Kidney Antibodies	>1438 publications with EGF and Kidney
Lung Antibodies	>1356 publications with EGF and Lung
Skin Antibodies	>1184 publications with EGF and Skin
Muscle Antibodies	>1159 publications with EGF and Muscle
Embryonic Tissue Antibodies	>997 publications with EGF and Embryonic Tissue
Mouth Antibodies	>808 publications with EGF and Mouth
Intestine Antibodies	>805 publications with EGF and Intestine
Eye Antibodies	>790 publications with EGF and Eye
Placenta Antibodies	>430 publications with EGF and Placenta