Hepatocellular Carcinoma Active Protein

Name: Active Protein; Hepatocellular Carcinoma; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS650134
Price: 370 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650134

Human Hemofiltrate CC chemokine-1 (HCC-1) was first isolated from the hemofiltrate of patients with chronic renal failure. HCC-1 has a 46% amino acid sequence identity with MIP-1a/MIP-1b and 29-37% homology with other CC chemokines. Recombinant Human HCC-1 is… More details

$370 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Hepatocellular Carcinoma, Active Protein

Full Product Name

Hepatocellular Carcinoma, Recombinant, Human (Hemofiltrate Carcinoma Chemokine, HCC-1)

Sequence

The sequence of the first five N-terminal amino acids was determined and was found to be Thr-Glu-Se r-Ser-Ser.

Host

E Coli

Form/Format

Supplied as a lyophilized powder. No additives.

Purity/Purification

Highly Purified
98% by RP-HPLC, FPLC, or reducing/non-reducing SDS-PAGE Silver Stain. Chromatographically purified.

Preparation and Storage

Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile dH2O and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer.

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

HCC-1 is fully biologically active when compared to standard. The Biological activity is calculated by its ability to chemoattract Human monocytes at 5.0-20.0ng/ml.

Dimers and Aggregates

1% as determined by silver-stained SDS-PAGE gel analysis.

Endotoxin Level

0.1ng/ug (IEU/ug) of Human HCC-1.

Protein Content

Protein quantitation was carried out by two independent methods:
1. UV spectroscopy at 280nm.
2. Analysis by RP-HPLC, using a calibrated solution of HCC-1 as a Reference Standard.

Reconstitution

Reconstitute the lyophilized Human HCC-1 in sterile 18MO-cm H2O not less than 100ug/ml, which can then be further diluted to other aqueous solutions.

Product Categories/Family for Hepatocellular Carcinoma active protein

Growth Factors; Cytokines; Growth Factors-HCC

Other Notes

Small volumes of Hepatocellular Carcinoma active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Hepatocellular Carcinoma purchase

MBS650134 is an active protein targeting Hepatocellular Carcinoma. Also known as Hepatocellular Carcinoma, Recombinant, Human (Hemofiltrate Carcinoma Chemokine, HCC-1). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Hepatocellular Carcinoma. It may not necessarily be applicable to this product.

NCBI GI #

18496390

NCBI Accession #

AAL74055.1

NCBI Official Full Name

hepatocellular carcinoma susceptibility protein

Protein Family

Protein N-lysine methyltransferase

UniProt Comments for Hepatocellular Carcinoma

YY1AP1: Enhances transcription activation by YY1. May play a role in cell cycle regulation. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription, coactivator/corepressor

Chromosomal Location of Human Ortholog: 1q22

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent; regulation of cell cycle

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.