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Betacellulin (BTC) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650210

Betacellulin is an EGF-related polypeptide growth factor that signals through the EGF receptor. It is produced in several tissues, including the pancreas, small intestine, and in certain tumor cells. Betacellulin is a potent mitogen for retinal pigment… More details

$370 / 0.005 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Betacellulin (BTC), Active Protein
Full Product Name
Betacellulin, Recombinant, Human
Product Gene Name
Host
E Coli
Form/Format
Supplied as lyophilized powder. Reconstitute in sterile ddH2O, to 0.1-1mg/ml, which can then be further diluted to other aqueous solutions
Purity/Purification
Highly Purified
98% by SDS-PAGE and HPLC analyses. Endoxoxin: 0.1EU/ug
Preparation and Storage
Lyophilized powder may be stored at 4 degree C for short-term only. Reconstitute to nominal volume by adding sterile ddH2O, aliquot and store at -20 degree C. Reconstituted product is stable for 12 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.Country of Origin:
USA
Molecular Weight
9.0kD
Chromosome Location
Chromosome: 4; NC_000004.11 (75671448..75719882, complement). Location: 4q13-q21
OMIM
600345
3D Structure
ModBase 3D Structure for P35070
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Specific Activity
2x10e7units/mg.
Biological Activity
The ED50 was determined by the dose-dependent stimulation of the proliferation of murine Balb/3T3 cells is 0.05ng/ml.

Other Notes

Small volumes of BTC active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for BTC purchase

MBS650210 is an active protein targeting BTC. Also known as Betacellulin, Recombinant, Human. Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for BTC. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
betacellulin
NCBI Official Synonym Full Names
betacellulin
NCBI Official Symbol
BTC
UniProt Protein Name
Probetacellulin
Protein Family
UniProt Gene Name
BTC
UniProt Entry Name
BTC_HUMAN
NCBI Protein Information
probetacellulin; OTTHUMP00000160600; OTTHUMP00000219057

NCBI Summary for BTC

The protein encoded by this gene is a member of the EGF family of growth factors. It is synthesized primarily as a transmembrane precursor, which is then processed to mature molecule by proteolytic events. This protein is a ligand for the EGF receptor. [provided by RefSeq]

UniProt Comments for BTC

Function: Potent mitogen for retinal pigment epithelial cells and vascular smooth muscle cells. The effects of betacellulin are probably mediated by the EGF receptor and other related receptors.

Subunit structure: Monomer.

Subcellular location: Betacellulin: Secreted › extracellular space. Probetacellulin: Cell membrane; Single-pass type I membrane protein.

Tissue specificity: Synthesized in several tissues and tumor cells. Predominantly expressed in pancreas and small intestine. Ref.3

Sequence similarities: Contains 1 EGF-like domain.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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