Lymphotactin (XCL1) Active Protein

Name: XCL1 Active Protein; Lymphotactin; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS650359
Price: 370 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650359

Lymphotactin is a newly discovered chemokine that exhibits chemotactic activity toward lymphocytes but not towards monocytes or neutrophils. Human lymphotactin is 10.2kD protein containing 92 amino acid residues. More details

$370 / 0.005 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Lymphotactin (XCL1), Active Protein

Full Product Name

Lymphotactin, Recombinant, Human (Small Inducible Cytokine Subfamily C Member 1, SCYC1, Chemokine C Motif Ligand 1, Ltn)

Product Gene Name

XCL1 active protein

Host

E Coli

Form/Format

Lyophilized protein with no additives. The protein may appear as a haze or film which is difficult to see at the bottom of the vial.

Purity/Purification

Molecular Biology Grade
> 98% by SDS-PAGE and HPLC analyses.

Preparation and Storage

The lyophilized protein is stable for a few weeks at RT. It is best stored at -20 degree C. Reconstituted lymphotactin should be stored in working aliquots at -20 degree C.

Molecular Weight

10.2kD

Chromosome Location

Chromosome: 1; NC_000001.10 (168545856..168551315). Location: 1q23

OMIM

600250

3D Structure

ModBase 3D Structure for P47992

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Determined by its ability to chemoattract human peripheral blood lymphocytes using a concentration range of 10-100ng/ml

Country of Origin

USA

Endotoxin Level

< 0.1ng per ug of lymphotactin.

Reconstitution

We recommend a quick spin followed by reconstitution in water to a concentration of 0.1-1.0mg/ml. This solution can then be diluted into other aqueous buffers.

Product Categories/Family for XCL1 active protein

Growth Factors; Cytokines; Growth Factors-Lymphotactin

Other Notes

Small volumes of XCL1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for XCL1 purchase

MBS650359 is an active protein targeting XCL1. Also known as Lymphotactin, Recombinant, Human (Small Inducible Cytokine Subfamily C Member 1, SCYC1, Chemokine C Motif Ligand 1, Ltn). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for XCL1. It may not necessarily be applicable to this product.

NCBI GI #

4506853

NCBI GeneID

6375

NCBI Accession #

NP_002986.1

UniProt Primary Accession #

P47992

UniProt Secondary Accession #

Q52MA8

UniProt Related Accession #

P47992

GenBank Nucleotide #

NM_002995.2

NCBI Official Full Name

lymphotactin

NCBI Official Synonym Full Names

chemokine (C motif) ligand 1

NCBI Official Symbol

XCL1

NCBI Official Synonym Symbols

LTN; ATAC; LPTN; SCM1; SCM-1; SCM1A; SCYC1; SCM-1a

UniProt Protein Name

Lymphotactin

UniProt Synonym Protein Names

ATAC; C motif chemokine 1; Cytokine SCM-1; Lymphotaxin; SCM-1-alpha; Small-inducible cytokine C1; XC chemokine ligand 1

Protein Family

Lymphotactin

UniProt Gene Name

XCL1

UniProt Synonym Gene Names

LTN; SCYC1

UniProt Entry Name

XCL1_HUMAN

NCBI Protein Information

lymphotactin; SCM-1-alpha; lymphotaxin; cytokine SCM-1; OTTHUMP00000032498; c motif chemokine 1; XC chemokine ligand 1; single cysteine motif 1a; small-inducible cytokine C1; small inducible cytokine subfamily C, member 1 (lymphotactin)

NCBI Summary for XCL1

This gene encodes a member of the chemokine superfamily. Chemokines function in inflammatory and immunological responses, inducing leukocyte migration and activation. The encoded protein is a member of the C-chemokine subfamily, retaining only two of four cysteines conserved in other chemokines, and is thought to be specifically chemotactic for T cells. This gene and a closely related family member are located on the long arm of chromosome 1. [provided by RefSeq]

UniProt Comments for XCL1

Function: Chemotactic activity for lymphocytes but not for monocytes or neutrophils.

Subcellular location: Secreted.

Tissue specificity: Highest level in spleen, lower in peripheral leukocytes and very low levels in lung, colon and small intestine.

Sequence similarities: Belongs to the intercrine gamma family.

Research Articles on XCL1

1. The expression patterns of XCR1 and XCL1 were conserved in human and mice blood cells, including certain dendritic cell subsets.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with XCL1 active protein

Reference Product	PubMed Publications
XCR1 active protein	>23 publications with XCL1 and XCR1

Pathways associated with XCL1 active protein

Products by Pathway	Pathway Diagram
Chemokine Receptors Bind Chemokines Pathway antibodies	Chemokine Receptors Bind Chemokines Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Chemokine Signaling Pathway antibodies	Chemokine Signaling Pathway Diagram
Class A/1 (Rhodopsin-like Receptors) Pathway antibodies	Class A/1 (Rhodopsin-like Receptors) Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
G Alpha (q) Signalling Events Pathway antibodies	G Alpha (q) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
Peptide Ligand-binding Receptors Pathway antibodies	Peptide Ligand-binding Receptors Pathway Diagram

Diseases associated with XCL1 active protein

Disease Name	Pubmed Publications
Inflammation Antibodies	>23 publications with XCL1 and Inflammation
Neoplasms, Experimental Antibodies	>14 publications with XCL1 and Neoplasms, Experimental
Necrosis Antibodies	>13 publications with XCL1 and Necrosis
Respiratory Tract Diseases Antibodies	>12 publications with XCL1 and Respiratory Tract Diseases
Hypersensitivity Antibodies	>10 publications with XCL1 and Hypersensitivity
Eye Diseases Antibodies	>4 publications with XCL1 and Eye Diseases
Multiple Myeloma Antibodies	>4 publications with XCL1 and Multiple Myeloma
Adenocarcinoma Antibodies	>3 publications with XCL1 and Adenocarcinoma
Kidney Diseases Antibodies	>3 publications with XCL1 and Kidney Diseases
Carcinoma, Squamous Cell Antibodies	>3 publications with XCL1 and Carcinoma, Squamous Cell

Organs/Tissues associated with XCL1 active protein

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>124 publications with XCL1 and Blood
Lung Antibodies	>14 publications with XCL1 and Lung
Liver Antibodies	>2 publications with XCL1 and Liver
Prostate Antibodies	>1 publications with XCL1 and Prostate