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Uridine-Cytidine Kinase 1-Like 1 (UCK1L) Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6504842

MBS6504842 is an antibody targeting UCK1L. Also known as Uridine-Cytidine Kinase 1-like 1, NT (UCK1L, UCK1-LIKE, Uridine-cytidine kinase-like 1, URKL1) (MaxLight 405). Reactive in Human. Host: Rabbit. More details

$1025 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Uridine-Cytidine Kinase 1-like 1 (UCK1L), Polyclonal Antibody
Full Product Name
Uridine-Cytidine Kinase 1-like 1, NT (UCK1L, UCK1-LIKE, Uridine-cytidine kinase-like 1, URKL1) (MaxLight 405)
Product Gene Name
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with MaxLight405.
Purity/Purification
Purified by Ammonium Sulfate Precipitation.
Specificity
Recognizes human URKL1.
Preparation and Storage
Store product at 4 degree C in the dark. DO NOT FREEZE! Stable at 4 degree C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: MaxLight405 conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Molecular Weight
61.141
OMIM
610866
3D Structure
ModBase 3D Structure for Q9NWZ5
Immunogen
Synthetic peptide selected from the N-terminal region of human URKL1 (KLH).
Conjugate
MaxLight405
Note
Preservative Free

Product Categories/Family for anti-UCK1L antibody

Applications Tested/Suitable for anti-UCK1L antibody
Immunohistochemistry (IHC), FLISA, Western Blot (WB)
Application Notes for anti-UCK1L antibody
IHC: 1:50-1:100
FLISA: 1:1,000
WB: 1:100-1:500
Applications are based on unconjugated antibody.

Western Blot (WB) of anti-UCK1L antibody

Western blot analysis of anti-URKL1 Pab in 293 cell line lysate (35ug/lane). URKL1(arrow) was detected using the purified Pab.
Rabbit Anti-UCK1L Polyclonal Antibody – Cat# MBS6504842

Immunohistochemistry (IHC) of anti-UCK1L antibody

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
Rabbit Anti-UCK1L Polyclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6504842

Product References and Citations for anti-UCK1L antibody

1. Kashuba, E., et al., (er) BMC Cell Biol. 3 (1), 23 (2002).

Other Notes

Small volumes of anti-UCK1L antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for UCK1L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
uridine-cytidine kinase-like 1 isoform 1
NCBI Official Synonym Full Names
uridine-cytidine kinase 1 like 1
NCBI Official Symbol
UCKL1
NCBI Official Synonym Symbols
UCK1L; URKL1
UniProt Protein Name
Uridine-cytidine kinase-like 1
UniProt Gene Name
UCKL1
UniProt Synonym Gene Names
URKL1
UniProt Entry Name
UCKL1_HUMAN
NCBI Protein Information
uridine-cytidine kinase-like 1

NCBI Summary for UCK1L

The protein encoded by this gene is a uridine kinase. Uridine kinases catalyze the phosphorylation of uridine to uridine monophosphate. This protein has been shown to bind to Epstein-Barr nuclear antigen 3 as well as natural killer lytic-associated molecule. Ubiquitination of this protein is enhanced by the presence of natural killer lytic-associated molecule. In addition, protein levels decrease in the presence of natural killer lytic-associated molecule, suggesting that association with natural killer lytic-associated molecule results in ubiquitination and subsequent degradation of this protein. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2014]
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UniProt Comments for UCK1L

UCKL1: May contribute to UTP accumulation needed for blast transformation and proliferation. Belongs to the uridine kinase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 2.7.1.48; Transferase; Nucleotide Metabolism - pyrimidine; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 20q13.33

Cellular Component: cytoplasm; nucleus

Molecular Function: protein binding; uridine kinase activity; ATP binding

Biological Process: viral reproduction; phosphorylation
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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