IFNB1 Recombinant Protein – Cat# MBS650588

Interferon Beta (IFNB1) Recombinant Protein

Name: IFNB1 Recombinant Protein; Interferon Beta; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS650588
Price: 975 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650588

Three types of interferons have been described: interferon-alpha (IFN-alpha), interferon-beta (IFN-beta), and interferon-gamma (IFN-gamma). An extensive variety of biological effects have been observed for the interferon family including antiviral activity;… More details

$975 / 50K Units +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Interferon beta (IFNB1), Recombinant Protein

Full Product Name

Interferon beta, Recombinant, Mouse (CHO) (IFNb)

Product Gene Name

IFNB1 recombinant protein

Host

Mouse, CHO-derived

Form/Format

Supplied as a lyophilized powder in PBS, 10% mouse albumin, 0.01% gelatin. Reconstitute the vial by injection of 1 ml distilled or de-ionized water (Caution: vial is under vacuum).

Purity/Purification

Purified
Purified

Preparation and Storage

Lyophilized powder may be stored at-20 degree C. Stable for 12 months at -20 degree C. Reconstitute with 1ml distilled or de-ionized water. Aliquot and store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. Note: mouse IFN-beta is highly labile when agitated.

Molecular Weight

22,294 Da

Chromosome Location

Chromosome: 9; NC_000009.11 (21077104..21077943, complement). Location: 9p21

OMIM

147640

3D Structure

ModBase 3D Structure for P01574

Product Categories/Family for IFNB1 recombinant protein

Growth Factors; Cytokines; Growth Factors-Interferon

Application Notes for IFNB1 recombinant protein

Dilution: For dilutions use a buffer containing 2% bovine serum albumin or culture medium. (Do not use fresh serum.)

Other Notes

Small volumes of IFNB1 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IFNB1 purchase

MBS650588 is a recombinant protein targeting IFNB1. Also known as Interferon beta, Recombinant, Mouse (CHO) (IFNb). Host: Mouse, CHO-derived.

Additional Details

NCBI/Uniprot data below describe general gene information for IFNB1. It may not necessarily be applicable to this product.

NCBI GI #

4504603

NCBI GeneID

3456

NCBI Accession #

NP_002167.1

UniProt Primary Accession #

P01574

UniProt Related Accession #

P01574; Q15943; Q5VWC9

GenBank Nucleotide #

NM_002176.2

NCBI Official Full Name

interferon beta

NCBI Official Synonym Full Names

interferon, beta 1, fibroblast

NCBI Official Symbol

IFNB1

NCBI Official Synonym Symbols

IFB; IFF; IFNB; MGC96956

UniProt Protein Name

Interferon beta

UniProt Synonym Protein Names

Fibroblast interferon

Protein Family

Interferon

UniProt Gene Name

IFNB1

UniProt Synonym Gene Names

IFB; IFNB

UniProt Entry Name

IFNB_HUMAN

NCBI Protein Information

interferon beta; IFN-beta; OTTHUMP00000021131; fibroblast interferon

UniProt Comments for IFNB1

Function: Has antiviral, antibacterial and anticancer activities.

Subunit structure: Monomer.

Subcellular location: Secreted.

Pharmaceutical use: Available under the names Avonex (Biogen), Betaseron (Berlex) and Rebif (Serono). Used in the treatment of multiple sclerosis (MS). Betaseron is a slightly modified form of IFNB1 with two residue substitutions.

Sequence similarities: Belongs to the alpha/beta interferon family.

Research Articles on IFNB1

1. The beta-interferon scaffold attachment region sustained the highest levels of H3 histone acetylation and transgene expression throughout the study.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IFNB1 recombinant protein

Reference Product	PubMed Publications
IFNAR2 recombinant protein	>1 publications with IFNB1 and IFNAR2
IFNAR1 recombinant protein	>1 publications with IFNB1 and IFNAR1

Pathways associated with IFNB1 recombinant protein

Products by Pathway	Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Chagas Disease (American Trypanosomiasis) Pathway antibodies	Chagas Disease (American Trypanosomiasis) Pathway Diagram
Cytokine Signaling In Immune System Pathway antibodies	Cytokine Signaling In Immune System Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokine-cytokine Receptor Interaction Pathway antibodies	Cytokine-cytokine Receptor Interaction Pathway Diagram
Cytokines And Inflammatory Response Pathway antibodies	Cytokines And Inflammatory Response Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Cytosolic DNA-sensing Pathway antibodies	Cytosolic DNA-sensing Pathway Diagram
Factors Involved In Megakaryocyte Development And Platelet Production Pathway antibodies	Factors Involved In Megakaryocyte Development And Platelet Production Pathway Diagram
Hemostasis Pathway antibodies	Hemostasis Pathway Diagram

Diseases associated with IFNB1 recombinant protein

Disease Name	Pubmed Publications
Neoplasms Antibodies	>7 publications with IFNB1 and Neoplasms
Carcinoma Antibodies	>4 publications with IFNB1 and Carcinoma
Leukemia Antibodies	>3 publications with IFNB1 and Leukemia
Autoimmune Diseases Antibodies	>3 publications with IFNB1 and Autoimmune Diseases
Inflammation Antibodies	>2 publications with IFNB1 and Inflammation
Glioma Antibodies	>2 publications with IFNB1 and Glioma
Congenital Abnormalities Antibodies	>2 publications with IFNB1 and Congenital Abnormalities
Carcinoma, Non-Small-Cell Lung Antibodies	>2 publications with IFNB1 and Carcinoma, Non-Small-Cell Lung
Carcinoma in Situ Antibodies	>2 publications with IFNB1 and Carcinoma in Situ
Nervous System Diseases Antibodies	>2 publications with IFNB1 and Nervous System Diseases