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Ciliary Neurotropic Factor, Rat (CNTF) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650610

Ciliary Neutrophic Factor (CNTF) is a potent neural factor originally characterized as a survival factor for chick ciliary neurons in vitro. CNTF is also important for the survival of other neural cell types including primary sensory neurons, motor neurons,… More details

$685 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Ciliary Neurotropic Factor, Rat (Cntf), Active Protein
Full Product Name
Ciliary Neurotropic Factor, Recombinant, Rat (CNTF)
Product Gene Name
Sequence
AFAEQTPLTL HRRDLCSRSI WLARKIRSDL TALMESYVKH QGLNKNINLD SVDGVPVAST DRWSEMTEAE RLQENLQAYR TFQGMLTKLL EDQRVHFTPT EGDFHQAIHT LMLQVSAFAY QLEELMVLLE QKIPENEADG MPATVGDGGL FEKKLWGLKV LQELSQWTVR SIHDLRVISS HQMGISALES HYGAKDKQM
Host
E Coli
Form/Format
Supplied as a lyophilized powder.
Purity/Purification
Highly Purified
~98% by SDS-PAGE and HPLC. Endotoxin: 0.1ng/ug (1EU/ug)
Preparation and Storage
Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile dH2O or PBS. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. Reconstituted product is stable for 6 months at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
22.7kD
Chromosome Location
Chromosome: 1; NC_005100.2 (215842668..215844691, complement). Location: 1q43
3D Structure
ModBase 3D Structure for P20294
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Determined by its ability to stimulate proliferation of human TF-1 cells using an ED50 concentration range of 25-35ng/ml.

Other Notes

Small volumes of Cntf active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Cntf purchase

MBS650610 is an active protein targeting Cntf. Also known as Ciliary Neurotropic Factor, Recombinant, Rat (CNTF). Host: E Coli.

Additional Details

NCBI/Uniprot data below describe general gene information for Cntf. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
ciliary neurotrophic factor
NCBI Official Synonym Full Names
ciliary neurotrophic factor
NCBI Official Symbol
Cntf
UniProt Protein Name
Ciliary neurotrophic factor
UniProt Gene Name
Cntf
UniProt Entry Name
CNTF_RAT
NCBI Protein Information
ciliary neurotrophic factor; ciliary neurotropic factor

NCBI Summary for Cntf

a cytokine involved in neuronal degeneration and adipocyte gene expression [RGD]

UniProt Comments for Cntf

Function: CNTF is a survival factor for various neuronal cell types. Seems to prevent the degeneration of motor axons after axotomy.

Subcellular location: Cytoplasm.

Tissue specificity: Nervous system.

Sequence similarities: Belongs to the CNTF family.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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