Fas Ligand (FASLG) Active Protein

Name: FASLG Active Protein; Fas Ligand; Research Grade; MyBioSource
Brand: MyBioSource
SKU: MBS650674
Price: 865 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650674

FasL is a type II membrane protein belonging to the TNF family of cytokines. FasL induces apoptosis when it binds to cells expressing the Fas antigen. FasL was first discovered on the cell surface of T cells and NK cells. Expressed on the cell surface of… More details

$865 / 0.002 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Fas Ligand (FASLG), Active Protein

Full Product Name

Fas Ligand, Recombinant, Human (FASL) (BSA Free)

Product Gene Name

FASLG active protein

Form/Format

Supplied as a lyophillized powder from PBS, pH 7.2.

Purity/Purification

Highly Purified
98% by SDS-PAGE

Preparation and Storage

Lyophilized powder may be stored at -20 degree C. Stable for 12 months at -20 degree C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degree C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

Molecular Weight

10,410 Da

Chromosome Location

Chromosome: 16; NC_007314.3 (36729078..36737098, complement). Location: 16q17

3D Structure

ModBase 3D Structure for Q9TTJ2

Active Protein Note

Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.

Biological Activity

Determined by its ability to induce cytotoxicity in Jurkat cells in the absence of any cross-linking. The ED50 for this effect is <10ng/ml, corresponding to a specific activity of >1x10e5 units/mg.

Endotoxin Level

0.1ng/ug (1EU/ug).

Reconstitution

Spin down product and reconstitute in water to a concentration of 0.1-1.0mg/ml.

Product Categories/Family for FASLG active protein

Growth Factors; Cytokines; Growth Factors-FasL

Other Notes

Small volumes of FASLG active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FASLG purchase

MBS650674 is an active protein targeting FASLG. Also known as Fas Ligand, Recombinant, Human (FASL) (BSA Free).

Additional Details

NCBI/Uniprot data below describe general gene information for FASLG. It may not necessarily be applicable to this product.

NCBI GI #

149643015

NCBI GeneID

407111

NCBI Accession #

NP_001092329.1

UniProt Primary Accession #

Q9TTJ2

UniProt Related Accession #

Q9TTJ2

GenBank Nucleotide #

NM_001098859.1

NCBI Official Full Name

Fas ligand

NCBI Official Symbol

FASLG

UniProt Protein Name

Fas ligand

Protein Family

Tumor necrosis factor ligand superfamily

UniProt Entry Name

Q9TTJ2_BOVIN

NCBI Protein Information

Fas ligand; CD95 ligand; APO-1 ligand; TNF superfamily, member 6

Research Articles on FASLG

1. activation of the Fas pathway and presence of FSH during in vitro maturation increased the incidence of apoptosis in cumulus cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FASLG active protein

Products by Pathway	Pathway Diagram
Activation Of Pro-Caspase 8 Pathway antibodies	Activation Of Pro-Caspase 8 Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
African Trypanosomiasis Pathway antibodies	African Trypanosomiasis Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Allograft Rejection Pathway antibodies	Allograft Rejection Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Apoptosis Pathway antibodies	Apoptosis Pathway Diagram
Autoimmune Thyroid Disease Pathway antibodies	Autoimmune Thyroid Disease Pathway Diagram

Organs/Tissues associated with FASLG active protein

Organ/Tissue Name	Pubmed Publications
Mixed Antibodies	>42 publications with FASLG and Mixed