IL-1R-1 Antibody – Goat Polyclonal

Two distinct receptors bind the pleiotropic cytokines IL-1a and IL-1b. The IL-1 Receptor I (IL-1 RI) is an 80kD transmembrane protein expressed predominantly in T cells, fibroblasts, and endothelial cells. IL-1 Receptor II is a 68kD protein that is found on B lymphocytes, neutrophils, monocytes, large granular leukocytes, and endothelial cells. Both receptors are members of the immunoglobulin superfamily and show ~28% sequence identity in their extracellular domains. The two receptors do not heterodimerize into a receptor complex. Soluble recombinant IL-1 Receptor I is a potent antagonist of IL-1 action.

Small volumes of anti-IL-1R-1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

MBS6507791 is an antibody targeting IL-1R-1. Also known as Interleukin 1 Receptor Type I (Interleukin Receptor 1, IL-1R-1, IL1R1, IL-1RT1, IL1RT1, Interleukin 1 Receptor alpha Type 1, IL-1R alpha, IL1RA, Antigen CD121a, CD121A, CD121a Antigen, D2S1473, IL-1R1, IL1 Inhibitor, P80)(APC). Reactive in Human. Host: Goat.