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Interleukin 32, 1-131aa (IL32) Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650808

Interleukin 32 isoform A belongs to cytokine family. This protein expression is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. It has the ability to induce proinflammatory cytokines such as TNF_ and IL8 in THP1… More details

$685 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Interleukin 32, 1-131aa (IL32), Recombinant Protein
Full Product Name
Interleukin 32, 1-131aa, Recombinant, Human (IL-32, Natural killer cells protein 4, NK4, Tumor necrosis factor alpha-inducing factor, TAIF)
Product Gene Name
Sequence
MRGSHHHHHH GMASMTGGQQ MGRDLYDDDD KDRWGSHMCF PKVLSDDMKK LKARMHQAIE RFYDKMQNAE SGRGQVMSSL AELEDDFKEG YLETVAAYYE EQHPELTPLL EKERDGLRCR GNRSPVPDVE DPATEEPGES FCDKSYGAPR GDKEELTPQK CSEPQSSK
Form/Format
Supplied as a liquid in 20mM Tris-HCl, pH8.0, 1mM DTT, 10% glycerol.
Purity/Purification
>95% (SDS-PAGE)
Concentration
1mg/ml (lot specific)
Preparation and Storage
May be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Molecular Weight
19.1kD (168aa)
Chromosome Location
Chromosome: 16; NC_000016.9 (3115313..3119668). Location: 16p13.3
OMIM
606001
3D Structure
ModBase 3D Structure for P24001
Endotoxin
<1EU/1ug (LAL)

SDS-Page of IL32 recombinant protein

15% SDS-PAGE of I8442-43A (3ug)
IL32 Recombinant Protein – Cat# MBS650808

Other Notes

Small volumes of IL32 recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL32 purchase

MBS650808 is a recombinant protein targeting IL32. Also known as Interleukin 32, 1-131aa, Recombinant, Human (IL-32, Natural killer cells protein 4, NK4, Tumor necrosis factor alpha-inducing factor, TAIF).

Additional Details

NCBI/Uniprot data below describe general gene information for IL32. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Interleukin 32
NCBI Official Synonym Full Names
interleukin 32
NCBI Official Symbol
IL32
NCBI Official Synonym Symbols
NK4; TAIF; TAIFa; TAIFb; TAIFc; TAIFd; IL-32beta; IL-32alpha; IL-32delta; IL-32gamma
UniProt Protein Name
Interleukin-32
UniProt Synonym Protein Names
Natural killer cells protein 4; Tumor necrosis factor alpha-inducing factor
Protein Family
UniProt Gene Name
IL32
UniProt Synonym Gene Names
NK4; TAIF
UniProt Entry Name
IL32_HUMAN
NCBI Protein Information
interleukin-32; OTTHUMP00000236040; OTTHUMP00000236041; OTTHUMP00000236042; OTTHUMP00000236043; OTTHUMP00000236044; OTTHUMP00000236045; OTTHUMP00000236046; OTTHUMP00000236047; OTTHUMP00000236048; OTTHUMP00000236049; OTTHUMP00000236050; OTTHUMP00000236051; OTTHUMP00000236052; OTTHUMP00000236053; OTTHUMP00000236054; interleukin-32 theta; natural killer cells protein 4; natural killer cell transcript 4; tumor necrosis factor alpha-inducing factor

NCBI Summary for IL32

This gene encodes a member of the cytokine family. The protein contains a tyrosine sulfation site, 3 potential N-myristoylation sites, multiple putative phosphorylation sites, and an RGD cell-attachment sequence. Expression of this protein is increased after the activation of T-cells by mitogens or the activation of NK cells by IL-2. This protein induces the production of TNFalpha from macrophage cells. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq]
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UniProt Comments for IL32

Function: Cytokine that may play a role in innate and adaptive immune responses. It induces various cytokines such as TNFA/TNF-alpha and IL8. It activates typical cytokine signal pathways of NF-kappa-B and p38 MAPK. Ref.2

Subcellular location: Secreted Ref.2.

Tissue specificity: Selectively expressed in lymphocytes. Expression more prominent in immunce cells than in non-immune cells. Ref.2

Induction: Expression increased after activation of T-cells by mitogens or activation of NK cells by IL2/interleukin-2. Ref.1
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with IL32 recombinant protein

 Reference Product  PubMed Publications
 PRTN3 recombinant protein  >5 publications with IL32 and PRTN3
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