• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

I-309 Recombinant (CCL1) Active Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS650934

Human I-309, an 8.5kD protein containing 74 amino acid residues, is a small glycoprotein secreted by activated T-lymphocytes and structurally related to other CC chemokines. More details

$370 / 0.002 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
I-309 Recombinant (CCL1), Active Protein
Full Product Name
I-309, Human Recombinant
Product Gene Name
Host
Recombinant human
Form/Format
Sterile filtered and lyophilized without additives.
Purity/Purification
Molecular Biology Grade
99% by SDS-PAGE and HPLC analyses.
Preparation and Storage
The lyophilized protein is stable at room temperature. Stored desiccated below 0 degree C. Reconstituted I-309 should be stored in working aliquots at- 20 degree C. Lyophilized Human I-309 can be reconstituted in water to a concentration of 1.0mg/ml. This solution can be diluted into other buffered solutions or stored at -20 degree C for future use.
Molecular Weight
8.5kD
Chromosome Location
Chromosome: 17; NC_000017.10 (32687399..32690252, complement). Location: 17q12
3D Structure
ModBase 3D Structure for Q76BR7
Active Protein Note
Protein activity can be an ambiguous term. Please refer to the data sheet or inquire with Technical Support to determine the definition of activity for this product.
Biological Activity
Determined by a chemotaxis assay using total human T cell population. Significant chemotaxis was achieved at a concentration range of 1-100ng/ml.
Endotoxin Level
0.1ng/ug

Other Notes

Small volumes of CCL1 active protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CCL1 purchase

MBS650934 is an active protein targeting CCL1. Also known as I-309, Human Recombinant. Host: Recombinant human.

Additional Details

NCBI/Uniprot data below describe general gene information for CCL1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
I-309
NCBI Official Synonym Full Names
chemokine (C-C motif) ligand 1
NCBI Official Symbol
CCL1
NCBI Official Synonym Symbols
P500; SISe; TCA3; I-309; SCYA1
UniProt Protein Name
I-309
Protein Family
UniProt Gene Name
SCYA1
UniProt Entry Name
Q76BR7_HUMAN
NCBI Protein Information
C-C motif chemokine 1; OTTHUMP00000163800; inflammatory cytokine I-309; small-inducible cytokine A1; T lymphocyte-secreted protein I-309; small inducible cytokine A1 (I-309, homologous to mouse Tca-3)

NCBI Summary for CCL1

This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine is secreted by activated T cells and displays chemotactic activity for monocytes but not for neutrophils. It binds to the chemokine receptor CCR8. [provided by RefSeq]
Show more

UniProt Comments for CCL1

CCL1: Cytokine that is chemotactic for monocytes but not for neutrophils. Binds to CCR8. Belongs to the intercrine beta (chemokine CC) family.

Protein type: Chemokine; Secreted, signal peptide; Motility/polarity/chemotaxis; Secreted

Chromosomal Location of Human Ortholog: 17q12

Cellular Component: extracellular space

Molecular Function: chemokine activity

Biological Process: cellular calcium ion homeostasis; viral reproduction; immune response; chemotaxis; signal transduction
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CCL1 active protein

 Reference Product  PubMed Publications
 CCR8 active protein  >81 publications with CCL1 and CCR8

Organs/Tissues associated with CCL1 active protein

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >18 publications with CCL1 and Lung
Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000