Cadherin, Neuronal (CDHN) ELISA Kit for Cat

Name: Cat CDHN ELISA Kit; Cadherin, Neuronal; MyBioSource
Brand: MyBioSource
SKU: MBS066528
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS066528

MBS066528 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Cadherin, Neuronal (CDHN) ELISA Kit target analytes in biological samples. The concentration gradients of the kit… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Cadherin, Neuronal (CDHN), ELISA Kit

Full Product Name

Cat Cadherin, Neuronal ELISA Kit

Product Gene Name

CDHN elisa kit

Species Reactivity

Cat

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

99,809 Da

OMIM

114020

3D Structure

ModBase 3D Structure for P19022

Other Notes

Small volumes of CDHN elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CDHN. It may not necessarily be applicable to this product.

NCBI GI #

119621646

NCBI GeneID

1000

NCBI Accession #

EAX01241.1

UniProt Primary Accession #

P19022

UniProt Secondary Accession #

Q14923; Q8N173; B0YIY6

UniProt Related Accession #

P19022

NCBI Official Full Name

cadherin 2, type 1, N-cadherin (neuronal), isoform CRA_b

NCBI Official Synonym Full Names

cadherin 2, type 1, N-cadherin (neuronal)

NCBI Official Symbol

CDH2

NCBI Official Synonym Symbols

CDHN; NCAD; CD325; CDw325

UniProt Protein Name

Cadherin-2

UniProt Synonym Protein Names

CDw325; Neural cadherin

UniProt Gene Name

CDH2

UniProt Synonym Gene Names

CDHN; NCAD; N-cadherin

UniProt Entry Name

CADH2_HUMAN

NCBI Protein Information

cadherin-2; N-cadherin 1; neural cadherin; neural-cadherin; cadherin 2, N-cadherin (neuronal); calcium-dependent adhesion protein, neuronal

NCBI Summary for CDHN

This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. The protein functions during gastrulation and is required for establishment of left-right asymmetry. At certain central nervous system synapses, presynaptic to postsynaptic adhesion is mediated at least in part by this gene product. [provided by RefSeq, Jul 2008]

UniProt Comments for CDHN

CDH2: Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. CDH2 may be involved in neuronal recognition mechanism. In hippocampal neurons, may regulate dendritic spine density. Interacts with CDCP1. Identified in a complex containing FGFR4, NCAM1, CDH2, PLCG1, FRS2, SRC, SHC1, GAP43 and CTTN. Interacts with PCDH8; this complex may also include TAOK2. The interaction with PCDH8 may lead to internalization through TAOK2/p38 MAPK pathway.

Protein type: Cell adhesion; Membrane protein, integral; Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 18q11.2

Cellular Component: focal adhesion; cell-cell adherens junction; lamellipodium; apical plasma membrane; integral to membrane; plasma membrane; synapse; intercellular junction; fascia adherens; catenin complex

Molecular Function: protein binding; gamma-catenin binding; beta-catenin binding; calcium ion binding; protein phosphatase binding; alpha-catenin binding

Biological Process: heterophilic cell adhesion; intercellular junction assembly and maintenance; muscle cell differentiation; cell migration; glial cell differentiation; positive regulation of MAPKKK cascade; calcium-dependent cell-cell adhesion; positive regulation of muscle cell differentiation; striated muscle cell differentiation; blood vessel morphogenesis; homophilic cell adhesion; cell adhesion

Research Articles on CDHN

1. N-cadherin had no diagnostic value in arrhythmogenic right ventricular cardiomyopathy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CDHN elisa kit

Reference Product	PubMed Publications
CTNNB1 elisa kit	>67 publications with CDHN and CTNNB1
MMP9 elisa kit	>9 publications with CDHN and MMP9
JUP elisa kit	>4 publications with CDHN and JUP
CTNNA1 elisa kit	>2 publications with CDHN and CTNNA1
CTNND1 elisa kit	>2 publications with CDHN and CTNND1
SPAG9 elisa kit	>1 publications with CDHN and SPAG9
LRP5 elisa kit	>1 publications with CDHN and LRP5
FGFR1 elisa kit	>1 publications with CDHN and FGFR1

Pathways associated with CDHN elisa kit

Products by Pathway	Pathway Diagram
Adherens Junctions Interactions Pathway antibodies	Adherens Junctions Interactions Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway antibodies	Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) Pathway Diagram
BDNF Signaling Pathway antibodies	BDNF Signaling Pathway Diagram
CDO In Myogenesis Pathway antibodies	CDO In Myogenesis Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Adhesion Molecules (CAMs) Pathway antibodies	Cell Adhesion Molecules (CAMs) Pathway Diagram
Cell Junction Organization Pathway antibodies	Cell Junction Organization Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram

Diseases associated with CDHN elisa kit

Disease Name	Pubmed Publications
Neoplasms Antibodies	>140 publications with CDHN and Neoplasms
Neoplasm Metastasis Antibodies	>36 publications with CDHN and Neoplasm Metastasis
Disease Progression Antibodies	>30 publications with CDHN and Disease Progression
Breast Neoplasms Antibodies	>23 publications with CDHN and Breast Neoplasms
Lung Neoplasms Antibodies	>20 publications with CDHN and Lung Neoplasms
Disease Models, Animal Antibodies	>19 publications with CDHN and Disease Models, Animal
Cardiovascular Diseases Antibodies	>18 publications with CDHN and Cardiovascular Diseases
Heart Diseases Antibodies	>13 publications with CDHN and Heart Diseases
Liver Diseases Antibodies	>12 publications with CDHN and Liver Diseases
Neoplasms, Experimental Antibodies	>12 publications with CDHN and Neoplasms, Experimental

Organs/Tissues associated with CDHN elisa kit

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>48 publications with CDHN and Brain