Mouse Anti-CD23 Monoclonal Antibody – Cat# MBS666366

CD23 Antibody – Mouse Monoclonal

Name: CD23 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS666366
Price: 380 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS666366

Information: Human CD23 is a low affinity receptor for IgE (Fc epsilon RII) found primarily on mature B cells and also on eosinophils, monocytes, dendritic cells, platelets, and a subset of thymic epithelial cells. CD23 interacts with CD21. Antibody BU38… More details

$380 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD23, Monoclonal Antibody

Full Product Name

anti-human CD23-Purified (with Antibiotics)

Product Gene Name

anti-CD23 antibody

Product Synonym Names

Monoclonal anti-human CD23(FcƒÕRIII)

Clonality

Monoclonal

Isotype

IgG1

Clone Number

BU38

Host

Mouse

Species Reactivity

Human

Form/Format

50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate

Purity/Purification

Purified (with Antibiotics)

Concentration

1.0 mg/ml (lot specific)

Preparation and Storage

Store at 2 - 5 degree C. Freeze/Thawing is not recommended.
Product should retain activity for at least 12 months after shipping date when stored as recommended.

Molecular Weight

35,126 Da

3D Structure

ModBase 3D Structure for Q63097

Performance

Five x 105 ficoll prepared human peripheral blood mononuclear cells were washed and preincubated 5 minutes with 20ul of 250ug/ml human IgG (To block non specific binding) after which they were washed and incubated 45 minutes on ice with 80 ul of anti-CD23 antibody at a concentration of 10 ug/ml. Cells were washed twice and incubated with 2 degree reagent Goat anti-Mouse IgG/FITC, after which they were washed three times, fixed and analyzed by FACS. A net 18% sub population of the cells stained positive with a mean shift of 0.57 log10 fluorescent unitswhen compared to a Mouse IgG1 negative control at a similar concentration.

Production

Antibody was Protein A purified from (low FBS containing) tissue culture supernatant. Purity was >95% Immunoglobulin by SDS-PAGE and contains less than 1% Bovine Immunoglobulin.

Buffer

50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5 mg/ml Gentamicin Sulfate (as a preservative).

Group Header

anti-human CD23

Immunogen

Human peripheral myeloma cells

Applications Tested/Suitable for anti-CD23 antibody

Flow Cytometry (FC/FACS), Western Blot (WB), FPS, Agonist

Product References and Citations for anti-CD23 antibody

Leukocyte Typing IV (W. Knapp, et al, eds.) Oxford University Press, Oxford, (1989) p. 67-81. D. L. Hardie, et al, (1993) Eur J Immunol 23: 997-1004. Leukocyte Typing V (S.F. Schlossman, et al, eds.) Oxford University Press, Oxford, (1995) p. 530-538. J.Y. Bonnefoy, et al, (1995) Curr Opin Immunol 7: 355-359.

Other Notes

Small volumes of anti-CD23 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD23 purchase

MBS666366 is an antibody targeting CD23. Also known as anti-human CD23-Purified (with Antibiotics). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for CD23. It may not necessarily be applicable to this product.

NCBI GI #

313673

NCBI GeneID

171075

NCBI Accession #

CAA51981.1

UniProt Primary Accession #

Q63097

NCBI Official Full Name

CD23

NCBI Official Synonym Full Names

Fc fragment of IgE, low affinity II, receptor for (CD23)

NCBI Official Symbol

Fcer2

NCBI Official Synonym Symbols

CD23; Fcer2a

UniProt Protein Name

CD23 protein

UniProt Synonym Protein Names

CD23 protein

Protein Family

Low affinity immunoglobulin epsilon Fc receptor

UniProt Gene Name

Fcer2

UniProt Entry Name

Q63097_RAT

NCBI Protein Information

low affinity immunoglobulin epsilon Fc receptor; Fcalpha RII; Fcalpha muR; Fc receptor alpha multiple ligand receptor; Fc receptor, IgE, low affinity II, alpha polypeptide

NCBI Summary for CD23

cell surface receptor; binds innumoglobulin (Ig)E and IgA antibodies [RGD, Feb 2006]

Research Articles on CD23

1. Immunohistochemical analyses suggested that the Fcalpha/muR isoform was expressed in the tubular epithelial cells, but not in the glomeruli.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CD23 antibody

Products by Pathway	Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Epstein-Barr Virus Infection Pathway antibodies	Epstein-Barr Virus Infection Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
Hematopoietic Cell Lineage Pathway antibodies	Hematopoietic Cell Lineage Pathway Diagram
IL-3 Signaling Pathway antibodies	IL-3 Signaling Pathway Diagram

Diseases associated with anti-CD23 antibody

Disease Name	Pubmed Publications
Asthma Antibodies	>17 publications with CD23 and Asthma
Lung Diseases Antibodies	>15 publications with CD23 and Lung Diseases
Respiratory Hypersensitivity Antibodies	>14 publications with CD23 and Respiratory Hypersensitivity
Hypersensitivity Antibodies	>14 publications with CD23 and Hypersensitivity
Hypersensitivity, Immediate Antibodies	>14 publications with CD23 and Hypersensitivity, Immediate
Inflammation Antibodies	>2 publications with CD23 and Inflammation
Carcinoma Antibodies	>1 publications with CD23 and Carcinoma
Intestinal Diseases Antibodies	>1 publications with CD23 and Intestinal Diseases
Hyperplasia Antibodies	>1 publications with CD23 and Hyperplasia
Bronchial Hyperreactivity Antibodies	>1 publications with CD23 and Bronchial Hyperreactivity

Organs/Tissues associated with anti-CD23 antibody

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>4 publications with CD23 and Lung
Spleen Antibodies	>1 publications with CD23 and Spleen