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CD271 Human Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS666855

Information: The p75 low affinity human Nerve Growth Factor receptor CD271(NGRF, TNFRSF16) is expressed on a variety of tissue types including a subset of splenic and nodal lymphocytes. Presence of this receptor supports uptake of intracellular calcium, but… More details

$605 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD271, Protein
Full Product Name
CD271(NGFR)-muIg-Purified (with Antibiotics)
Product Gene Name
CD271 protein
Product Synonym Names
Human CD271 NGFR(p75)-muIg Fusion Protein
Host
CHO cells
Species Reactivity
Human
Form/Format
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5% Gentamicin sulfate
Purity/Purification
Purified (with Antibiotics)
Concentration
0.5 mg/ml (lot specific)
Preparation and Storage
Store at 2 - 5 degree C. Freeze/Thawing is not recommended.
Product should retain activity for at least 6 months after shipping date when stored as recommended.
Molecular Structure
A soluble fusion protein consisting of the extracellular (195aa) domain of human NGFR fused to murine IgG2a Fc (233aa). N-teminal sequence: (29)KEACP
Transfectant Cell Line
CHO
Performance
Identity of NGFR-muIg was confirmed by n-terminal sequencing (KEACP). NGFR-muIg was reactive in EIA using plates coated with 1 ug/ml NGFb, and secondary detection with GAM/HRP. A signal was observed using 100 ng/ml NGFR-muIg.
Production
Recombinant protein from (low FBS containing) tissue culture supernatant of transfectants was purified using affinity and size exclusion chromatography.
Buffer
50 mM Sodium Phosphate pH 7.5, 100 mM Potassium Chloride, 150mM NaCl, 0.5 mg/ml Gentamicin Sulfate (as a preservative).
Group Header
CD271(NGFR)-muIg
Applications Tested/Suitable for CD271 protein
ELISA (EIA)

Product References and Citations for CD271 protein

1) Brodie C, E W Gelfand (1992) Journal of Immunology. 148(11): 3492-3497. 2) Fantini F, O. Johansson (1992) Journal of Investigative Dermatology. 99(6): 734-742. 3) Jiang H, G Gurogg, et al.(1999) J Biol Chem 274(37): 26209-16. 4) Khwaja F, D Djakiew, et al (2004) Cancer Res 64(17): 6207-13. 5) Flores-Torales E, Cuneo-Pareto S, et al. (2010) Folia Histochem Cytobiol. 48(4):682-6. 6) Kuçi S, Bader P, et al. (2010) Haematologica. 95(4):651-9. 7) Hermida-Gómez T, Blanco FJ, et al. (2011) Tissue Eng Part A. 17(7-8):1169-79. 8) Jones E, McGonagle D, et al. (2010) Arthritis Rheum. 62(7):1944-54. 9) Boiko AD, Weissman IL. Et al. (2010) Nature 466(7302):133-7. 10) Civenni G, Sommer L, et al. (2011) Cancer Res. 71(8):3098-109. 11) Mikami Y, Honda MJ, et al. (2011) Stem Cells Dev. 20(5):901-13.

Other Notes

Small volumes of CD271 protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CD271 purchase

MBS666855 is a protein targeting CD271. Also known as CD271(NGFR)-muIg-Purified (with Antibiotics). Reactive in Human. Host: CHO cells.
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