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IL-36R Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668412

IL-36R is a member of the IL-1 receptor family that has been associated with various inflammation-associated diseases. Ligands binding to IL-36R subsequently recruit the IL-1RAcP (IL-1 Receptor Accessory Protein) forming a heterodimeric signaling complex. The… More details

$210 / 0.025 mg +1 FREE 8GB USB
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
IL-36R, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to IL-36R (Clone: ABM47A2)
Product Gene Name
Product Synonym Names
IL1RL2; IL1RRP2; IL-36 receptor; IL-1Rrp2; Interleukin-1 receptor-related protein 2; Antibody to IL-36R; Anti-IL-36R Antibody; IL-36R Antibody
Clonality
Monoclonal
Isotype
IgG2b, kappa
Clone Number
ABM47A2
Host
Mouse
Species Reactivity
Human
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Purified
Protein G Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
OMIM
AF284434 mRNA
3D Structure
ModBase 3D Structure for Q9HB29
Immunogen Information
A partial length recombinant IL-36R protein (amino acids 1-203) was used as the immunogen for this antibody.
Antigen
IL-36R

Product Categories/Family for anti-IL-36R antibody

Applications Tested/Suitable for anti-IL-36R antibody
Western Blot (WB), Flow Cytometry (FC)
Application Notes for anti-IL-36R antibody
WB: 2-4 ug/ml
FC: 0.5-1ug/^106 Cells

Western Blot (WB) of anti-IL-36R antibody

Fig-1: Western blot analysis of IL-36R. Anti-IL-36R antibody (Clone: ABM47A2) was tested at 2 ug/ml on human Small Intestine lysate.
Mouse Anti-IL-36R Monoclonal Antibody – Cat# MBS668412

Flow Cytometry (FC) of anti-IL-36R antibody

Figure-2: Intracellular Flow cytometric analysis of IL-36R in K562 cells using 0.5 µg/10^6 Cells of IL-36R antibody (Clone: ABM47A2). Green represent isotype control and red represent Anti- IL36R antibody. (MBS668412). Goat Anti-Mouse PE conjugated was used as secondary antibody.
Mouse Anti-IL-36R Monoclonal Antibody, Flow Cytometry (FC) – Cat# MBS668412

Other Notes

Small volumes of anti-IL-36R antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for IL-36R purchase

MBS668412 is an antibody targeting IL-36R. Also known as Monoclonal Antibody to IL-36R (Clone: ABM47A2). Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-36R. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Interleukin-1 receptor-like 2
NCBI Official Synonym Full Names
interleukin 1 receptor like 2
NCBI Official Symbol
IL1RL2
NCBI Official Synonym Symbols
IL-36R; IL1RRP2; IL-1Rrp2; IL1R-rp2
UniProt Protein Name
Interleukin-1 receptor-like 2
UniProt Synonym Protein Names
IL-36 receptor; IL-36R; Interleukin-1 receptor-related protein 2; IL-1Rrp2; IL1R-rp2
UniProt Gene Name
IL1RL2
UniProt Synonym Gene Names
IL1RRP2; IL-36R; IL-1Rrp2; IL1R-rp2
NCBI Protein Information
interleukin-1 receptor-like 2

NCBI Summary for IL-36R

The protein encoded by this gene is a member of the interleukin 1 receptor family. An experiment with transient gene expression demonstrated that this receptor was incapable of binding to interleukin 1 alpha and interleukin 1 beta with high affinity. This gene and four other interleukin 1 receptor family genes, including interleukin 1 receptor, type I (IL1R1), interleukin 1 receptor, type II (IL1R2), interleukin 1 receptor-like 1 (IL1RL1), and interleukin 18 receptor 1 (IL18R1), form a cytokine receptor gene cluster in a region mapped to chromosome 2q12. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL-36R

IL1RL2: Receptor for interleukin 1 family member 9 (IL1F9). Binding to the agonist leads to the activation of NF-kappa-B. Belongs to the interleukin-1 receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 2q12.1

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: interleukin-1 receptor activity

Biological Process: cellular defense response; signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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