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DLL4 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668628

Dll4 (Delta-like 4), a membrane-bound Notch ligand, plays a fundamental role in vascular development and angiogenesis. It is highly expressed in capillary endothelial tip cells and is involved in suppressing neighboring stalk cells to become tip cells during… More details

$200 / 0.025 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DLL4, Polyclonal Antibody
Full Product Name
Polyclonal Antibody to DLL4
Product Gene Name
Product Synonym Names
DLL4; UNQ1895/PRO4341; Drosophila Delta homolog 4; Antibody to DLL4; Anti-DLL4 Antibody; DLL4 Antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Predicted: Mouse
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Purified
Protein A Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
Molecular Weight
74,605 Da
OMIM
AF253468 mRNA
3D Structure
ModBase 3D Structure for Q9NR61
Immunogen Information
A partial length recombinant DLL4 protein (amino acids 423-650) was used as the immunogen for this antibody.
Antigen
DLL4
Applications Tested/Suitable for anti-DLL4 antibody
Western Blot (WB)
Application Notes for anti-DLL4 antibody
WB: 2-4 ug/ml

Testing Data of anti-DLL4 antibody

Fig-1: Expression analysis of DLL4. Anti-DLL4 antibody (11-10033) was used at 2 ug/ml on A549 lysate.
Rabbit Anti-DLL4 Polyclonal Antibody – Cat# MBS668628

Other Notes

Small volumes of anti-DLL4 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DLL4 purchase

MBS668628 is an antibody targeting DLL4. Also known as Polyclonal Antibody to DLL4. Reactive in Human
Predicted: Mouse. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DLL4. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Delta-like protein 4
NCBI Official Synonym Full Names
delta like canonical Notch ligand 4
NCBI Official Symbol
DLL4
NCBI Official Synonym Symbols
AOS6; hdelta2
UniProt Protein Name
Delta-like protein 4
UniProt Synonym Protein Names
Drosophila Delta homolog 4; Delta4
Protein Family
UniProt Gene Name
DLL4
UniProt Synonym Gene Names
Delta4
NCBI Protein Information
delta-like protein 4

NCBI Summary for DLL4

This gene is a homolog of the Drosophila delta gene. The delta gene family encodes Notch ligands that are characterized by a DSL domain, EGF repeats, and a transmembrane domain. [provided by RefSeq, Jul 2008]

UniProt Comments for DLL4

DLL4: Plays a role in the Notch signaling pathway. Activates Notch-1 and Notch-4. Binds to Notch-1 and Notch-4. Expressed in vascular endothelium.

Protein type: Cell development/differentiation; Membrane protein, integral

Chromosomal Location of Human Ortholog: 15q15.1

Cellular Component: plasma membrane

Molecular Function: protein binding

Biological Process: angiogenesis; blood circulation; blood vessel remodeling; negative regulation of cell proliferation; negative regulation of Notch signaling pathway; negative regulation of transcription from RNA polymerase II promoter; Notch receptor processing; Notch signaling pathway; patterning of blood vessels; positive regulation of Notch signaling pathway; signal transduction; T cell differentiation

Disease: Adams-oliver Syndrome 6
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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