• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

NKX2-2 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668730

MBS668730 is an antibody targeting NKX2-2. Also known as Polyclonal Antibody to NKx2.2. Reactive in Human. Host: Rabbit. More details

$200 / 0.025 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NKx2.2 (NKX2-2), Polyclonal Antibody
Full Product Name
Polyclonal Antibody to NKx2.2
Product Gene Name
Product Synonym Names
NKX2.2; NKX2B; NKX2-2; Homeobox protein Nkx-2.2; Homeobox protein NK-2 homolog B
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Purified
Protein A Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
Molecular Weight
30,133 Da
3D Structure
ModBase 3D Structure for O95096
Immunogen Information
A partial length recombinant NKX2.2 protein (amino acids 1-250) was used as the immunogen for this antibody.
Antigen
NKX2.2

Product Categories/Family for anti-NKX2-2 antibody

Applications Tested/Suitable for anti-NKX2-2 antibody
Western Blot (WB)
Application Notes for anti-NKX2-2 antibody
WB: 2-4 ug/ml

Western Blot (WB) of anti-NKX2-2 antibody

Fig-1: Western blot analysis of NKx2.2. Anti-NKx2.2 antibody (11-7578) was used at 2 ug/ml on h Brain lysate.
Rabbit Anti-NKX2-2 Polyclonal Antibody – Cat# MBS668730

Other Notes

Small volumes of anti-NKX2-2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NKX2-2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homeobox protein Nkx-2.2
NCBI Official Synonym Full Names
NK2 homeobox 2
NCBI Official Symbol
NKX2-2
NCBI Official Synonym Symbols
NKX2B; NKX2.2
UniProt Protein Name
Homeobox protein Nkx-2.2
UniProt Synonym Protein Names
Homeobox protein NK-2 homolog B
Protein Family
UniProt Gene Name
NKX2-2
UniProt Synonym Gene Names
NKX2.2; NKX2B
NCBI Protein Information
homeobox protein Nkx-2.2

NCBI Summary for NKX2-2

The protein encoded by this gene contains a homeobox domain and may be involved in the morphogenesis of the central nervous system. This gene is found on chromosome 20 near NKX2-4, and these two genes appear to be duplicated on chromosome 14 in the form of TITF1 and NKX2-8. The encoded protein is likely to be a nuclear transcription factor. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for NKX2-2

NKX2-2: Acts as a transcriptional activator. Required for the maintenance of NEUROD1 expression in the horomone-producing endocrine cells of the pancreas. May be involved in specifying diencephalic neuromeric boundaries, and in controlling the expression of genes that play a role in axonal guidance. Associates with chromatin at the NEUROD1 promoter region. Binds to a subset of consensus elements within the NEUROD1 promoter. Belongs to the NK-2 homeobox family.

Protein type: Cell development/differentiation; Transcription factor

Chromosomal Location of Human Ortholog: 20p11.22

Cellular Component: nucleoplasm

Molecular Function: chromatin binding; transcription coactivator activity

Biological Process: brain development; endocrine pancreas development; positive regulation of transcription factor activity
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-NKX2-2 antibody

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000