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REG3A Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668766

Regenerating islet-derived protein 3-alpha (REG3A), also known as hepatocarcinoma-intestine-pancreas/ pancreatitis-associated protein (HIP/PAP), is a secreted intestinal antimicrobial protein that functions in the control of the bacterial proliferation. It is… More details

$200 / 0.025 mg +1 FREE 8GB USB
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Sample Manual Insert View PDF
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Testing Data View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
REG3A, Polyclonal Antibody
Full Product Name
Polyclonal Antibody to REG3A
Product Gene Name
anti-REG3A antibody
Product Synonym Names
REG3A; HIP; PAP; PAP1; Hepatointestinal pancreatic protein; Human proislet peptide; Pancreatitis-associated protein 1; Reg III-alpha; Regenerating islet-derived protein III-alpha; Antibody to REG3A; Anti-REG3A Antibody; REG3A Antibody
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Purified
Protein A Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
Molecular Weight
19,395 Da
OMIM
D13510 mRNA
3D Structure
ModBase 3D Structure for Q06141
Immunogen Information
A full length recombinant REG3A protein was used as the immunogen for this antibody.
Antigen
REG3A

Product Categories/Family for anti-REG3A antibody

Antibodies; Immunology
Applications Tested/Suitable for anti-REG3A antibody
Western Blot (WB)
Application Notes for anti-REG3A antibody
WB: 0.1-0.5 ug/ml

Western Blot (WB) of anti-REG3A antibody

Fig-1: Westren blot analysis of REG3A. Anti-REG3A antibody (11-4064) was used at 0.1 ug/ml on h Intestine lysate.
Rabbit Anti-REG3A Polyclonal Antibody – Cat# MBS668766

Other Notes

Small volumes of anti-REG3A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for REG3A purchase

MBS668766 is an antibody targeting REG3A. Also known as Polyclonal Antibody to REG3A. Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for REG3A. It may not necessarily be applicable to this product.

NCBI GI #
464341
NCBI GeneID
5068
NCBI Accession #
Q06141.1
UniProt Primary Accession #
Q06141
UniProt Related Accession #
Q06141
NCBI Official Full Name
Regenerating islet-derived protein 3-alpha
NCBI Official Synonym Full Names
regenerating family member 3 alpha
NCBI Official Symbol
REG3A
NCBI Official Synonym Symbols
HIP; PAP; PAP1; REG3; INGAP; PAP-H; PBCGF; HIP/PAP; REG-III
UniProt Protein Name
Regenerating islet-derived protein 3-alpha
UniProt Synonym Protein Names
Hepatointestinal pancreatic protein; HIP/PAP
Protein Family
Regenerating islet-derived protein
UniProt Gene Name
REG3A
UniProt Synonym Gene Names
HIP; PAP; PAP1; REG-3-alpha; HIP/PAP; Reg III-alpha
NCBI Protein Information
regenerating islet-derived protein 3-alpha

NCBI Summary for REG3A

This gene encodes a pancreatic secretory protein that may be involved in cell proliferation or differentiation. It has similarity to the C-type lectin superfamily. The enhanced expression of this gene is observed during pancreatic inflammation and liver carcinogenesis. The mature protein also functions as an antimicrobial protein with antibacterial activity. Alternate splicing results in multiple transcript variants that encode the same protein.[provided by RefSeq, Nov 2014]
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UniProt Comments for REG3A

REG3A: Might be a stress protein involved in the control of bacterial proliferation.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 2p12

Cellular Component: cytoplasm; extracellular space

Molecular Function: protein binding

Biological Process: cell proliferation; heterophilic cell adhesion; multicellular organismal development; negative regulation of keratinocyte differentiation
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Research Articles on REG3A

1. Up-regulation of REG3A correlates with colorectal cancer risk.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-REG3A antibody

 Reference Product  PubMed Publications
 REG1A antibody  >6 publications with REG3A and REG1A

Diseases associated with anti-REG3A antibody

 Disease Name  Pubmed Publications
 Carcinoma Antibodies  >7 publications with REG3A and Carcinoma
 Inflammation Antibodies  >7 publications with REG3A and Inflammation
 Adenocarcinoma Antibodies  >5 publications with REG3A and Adenocarcinoma
 Pancreatic Neoplasms Antibodies  >3 publications with REG3A and Pancreatic Neoplasms
 Liver Neoplasms Antibodies  >3 publications with REG3A and Liver Neoplasms
 Carcinoma, Hepatocellular Antibodies  >3 publications with REG3A and Carcinoma, Hepatocellular
 Disease Models, Animal Antibodies  >2 publications with REG3A and Disease Models, Animal
 Liver Cirrhosis Antibodies  >2 publications with REG3A and Liver Cirrhosis
 Insulin Resistance Antibodies  >1 publications with REG3A and Insulin Resistance
 Colonic Neoplasms Antibodies  >1 publications with REG3A and Colonic Neoplasms

Organs/Tissues associated with anti-REG3A antibody

 Organ/Tissue Name  Pubmed Publications
 Pancreas Antibodies  >10 publications with REG3A and Pancreas
 Liver Antibodies  >5 publications with REG3A and Liver
 Intestine Antibodies  >5 publications with REG3A and Intestine
 Stomach Antibodies  >1 publications with REG3A and Stomach
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