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TLR9 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668951

TLR9, a member of toll-like receptor family are central to the innate immunity by identifying pathogen associated molecular patterns (PAMPs). TLR9 identify unmethylated CpG dinucleotides present in bacterial DNA leading to NF-kB activation. More details

$210 / 25 Tests +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
TLR9, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to TLR9 (Clone: ABM1C51) PE conjugated
Product Gene Name
Product Synonym Names
TLR9; UNQ5798/PRO19605; CD289
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
ABM1C51
Host
Mouse
Species Reactivity
Mouse, Human
Form/Format
0.04mg/ml in PBS with 0.05% Azide.
Purity/Purification
Purified
Protein G Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
Molecular Weight
114,237 Da
OMIM
AF259262 mRNA
3D Structure
ModBase 3D Structure for Q9NR96
Antigen
TLR9
Immunogen Information
A partial length recombinant TLR9 protein (amino acids 100-290) was used as the immunogen for the antibody.
Conjugation
PE

Product Categories/Family for anti-TLR9 antibody

Applications Tested/Suitable for anti-TLR9 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-TLR9 antibody
FC/FACS analysis: 0.5 -1 ug/10^6 cells

Flow Cytometry (FC/FACS) of anti-TLR9 antibody

Fig-1: Intracellular flow analysis of TLR9 PE conjugated in hPBMC (Lymphocytes) using 0.5 ug/10^6 cells of TLR9 PE conjugated antibody (Clone: ABM1C51). Green represents isotype control; red represents anti-TLR9 PE conjugated antibody.
Mouse Anti-TLR9 Monoclonal Antibody – Cat# MBS668951

Other Notes

Small volumes of anti-TLR9 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TLR9 purchase

MBS668951 is an antibody targeting TLR9. Also known as Monoclonal Antibody to TLR9 (Clone: ABM1C51) PE conjugated. Reactive in Mouse, Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TLR9. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
toll-like receptor 9
NCBI Official Synonym Full Names
toll like receptor 9
NCBI Official Symbol
TLR9
NCBI Official Synonym Symbols
CD289
UniProt Protein Name
Toll-like receptor 9
UniProt Synonym Protein Names
CD_antigen: CD289
Protein Family
UniProt Gene Name
TLR9
NCBI Protein Information
toll-like receptor 9

NCBI Summary for TLR9

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family, which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. Studies in mice and human indicate that this receptor mediates cellular response to unmethylated CpG dinucleotides in bacterial DNA to mount an innate immune response. [provided by RefSeq, Aug 2017]
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UniProt Comments for TLR9

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR9 is a nucleotide-sensing TLR which is activated by unmethylated cytidine-phosphate-guanosine (CpG) dinucleotides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response (PubMed:11564765, PubMed:17932028). Controls lymphocyte response to Helicobacter infection (). Upon CpG stimulation, induces B-cell proliferation, activation, survival and antibody production (PubMed:23857366).
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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