• Call +1.858.633.0165 or Fax +1.858.633.0166 or Contact Us

TLR7 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668961

TLR7 (Toll-like receptor 7) is a member of the Toll-like receptor (TLR) family. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA; which plays a fundamental role in pathogen recognition and activation of innate immunity. TLR7 controls… More details

$210 / 0.025 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TLR7, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to TLR7 (Clone: ABM2C27) FITC Conjugated
Product Gene Name
Product Synonym Names
TLR7; UNQ248/PRO285
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
ABM2C27
Host
Mouse
Species Reactivity
Human
Form/Format
0.2 mg/ml in Tris buffer containing 0.05% Azide
Purity/Purification
Purified; Protein G Chromatography
Preparation and Storage
Store the antibody at 4 degree C; stable for 6 months.
OMIM
AF240467 mRNA
3D Structure
ModBase 3D Structure for Q9NYK1
Immunogen Information
A partial length recombinant human TLR7 protein (amino acids 500-900) was used as the immunogen for this antibody.
Conjugate
FITC

Product Categories/Family for anti-TLR7 antibody

Applications Tested/Suitable for anti-TLR7 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-TLR7 antibody
FC/FACS analysis: 0.5-1 ug/10^6 cells

Flow Cytometry (FC/FACS) of anti-TLR7 antibody

Fig: 1- Intracellular flow analysis of TLR7-FITC conjugated in THP1 cells using 0.5 ug/10^6 cells of TLR7-FITC antibody (Clone: ABM2C27). Green represents isotype control; red represents anti- TLR7-FITC antibody.
Mouse Anti-TLR7 Monoclonal Antibody – Cat# MBS668961

Other Notes

Small volumes of anti-TLR7 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for TLR7 purchase

MBS668961 is an antibody targeting TLR7. Also known as Monoclonal Antibody to TLR7 (Clone: ABM2C27) FITC Conjugated. Reactive in Human. Host: Mouse.

Additional Details

NCBI/Uniprot data below describe general gene information for TLR7. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
toll-like receptor 7
NCBI Official Synonym Full Names
toll like receptor 7
NCBI Official Symbol
TLR7
NCBI Official Synonym Symbols
TLR7-like
UniProt Protein Name
Toll-like receptor 7
Protein Family
UniProt Gene Name
TLR7
NCBI Protein Information
toll-like receptor 7

NCBI Summary for TLR7

The protein encoded by this gene is a member of the Toll-like receptor (TLR) family which plays a fundamental role in pathogen recognition and activation of innate immunity. TLRs are highly conserved from Drosophila to humans and share structural and functional similarities. They recognize pathogen-associated molecular patterns (PAMPs) that are expressed on infectious agents, and mediate the production of cytokines necessary for the development of effective immunity. The various TLRs exhibit different patterns of expression. This gene is predominantly expressed in lung, placenta, and spleen, and lies in close proximity to another family member, TLR8, on chromosome X. [provided by RefSeq, Jul 2008]
Show more

UniProt Comments for TLR7

Key component of innate and adaptive immunity. TLRs (Toll-like receptors) control host immune response against pathogens through recognition of molecular patterns specific to microorganisms. TLR7 is a nucleotide-sensing TLR which is activated by single-stranded RNA. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response ().
Show more

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Request a Quote

Please fill out the form below and our representative will get back to you shortly.

MBS000000
Contact Us

Please fill out the form below and our representative will get back to you shortly.

MBS000000