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IL-17C Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668974

MBS668974 is an antibody targeting IL-17C. Also known as Monoclonal Antibody to IL-17C (Clone: ABM25F3). Reactive in Human. Host: Mouse. More details

$210 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL-17C, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to IL-17C (Clone: ABM25F3)
Product Gene Name
Product Synonym Gene Name
IL21
Product Synonym Names
Interleukin-21; Za11; IL-17C
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
ABM25F3
Host
Mouse
Species Reactivity
Human
Form/Format
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Purified
Protein G Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeat freezing and thawing
Molecular Weight
16,867 Da
OMIM
AF254069 mRNA
3D Structure
ModBase 3D Structure for Q9HBE4
Antigen
Interleukin-17C
Immunogen Information
Full length recombinant protein of Interleukin-17C was used as the immunogen of this antibody.
Conjugation
Unconjugated

Product Categories/Family for anti-IL-17C antibody

Applications Tested/Suitable for anti-IL-17C antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-IL-17C antibody
FC/FC/FACS: 2-4 ug/cells10^6 

Testing Data of anti-IL-17C antibody

Figure-1: Intracellular staining of IL-17C in PC3 cell line using 2 ug/10^6 cells of IL-17C. Green represents isotype control; red represents Anti-IL-17C. Goat anti-mouse PE conjugate was used as secondary antibody.
Mouse Anti-IL-17C Monoclonal Antibody – Cat# MBS668974

Other Notes

Small volumes of anti-IL-17C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL-17C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
interleukin-21 isoform 2
NCBI Official Synonym Full Names
interleukin 21
NCBI Official Symbol
IL21
NCBI Official Synonym Symbols
Za11; IL-21; CVID11
UniProt Protein Name
Interleukin-21
UniProt Synonym Protein Names
Za11
Protein Family
UniProt Gene Name
IL21
UniProt Synonym Gene Names
IL-21
NCBI Protein Information
interleukin-21

NCBI Summary for IL-17C

This gene encodes a member of the common-gamma chain family of cytokines with immunoregulatory activity. The encoded protein plays a role in both the innate and adaptive immune responses by inducing the differentiation, proliferation and activity of multiple target cells including macrophages, natural killer cells, B cells and cytotoxic T cells. Dysregulation of this gene plays a role in multiple immune-mediated diseases including lupus, psoriasis and chronic inflammatory diseases. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2011]
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UniProt Comments for IL-17C

Cytokine with immunoregulatory activity. May promote the transition between innate and adaptive immunity. Induces the production of IgG1 and IgG3 in B-cells (). May play a role in proliferation and maturation of natural killer (NK) cells in synergy with IL15. May regulate proliferation of mature B- and T-cells in response to activating stimuli. In synergy with IL15 and IL18 stimulates interferon gamma production in T-cells and NK cells. During T-cell mediated immune response may inhibit dendritic cells (DC) activation and maturation.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-IL-17C antibody

 Reference Product  PubMed Publications
 IL21R antibody  >294 publications with IL-17C and IL21R
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