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mCD16/32 Antibody – Rat Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS668993

MBS668993 is an antibody targeting mCD16/32. Also known as Monoclonal Antibody to mCD16/32 (Clone: 2.4G2). Reactive in Mouse. Host: Rat. More details

$185 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
mCD16/32, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to mCD16/32 (Clone: 2.4G2)
Product Gene Name
Product Synonym Gene Name
Fcgr2
Product Synonym Names
Fc gamma receptor IIB; IgG Fc receptor II beta; Lymphocyte antigen 17; Fcgr2b; Ly-17; /Low affinity immunoglobulin gamma Fc region receptor III; FcRIII
Clonality
Monoclonal
Isotype
IgG2b
Clone Number
2.4G2
Host
Rat
Species Reactivity
Mouse
Form/Format
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Purified
Protein G Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeat freezing and thawing
Molecular Weight
– Da
3D Structure
ModBase 3D Structure for P08101
Antigen
mCD16/32
Immunogen Information
Mouse BALB/c Macrophage J774 Cell Line
Conjugation
Unconjugated

Product Categories/Family for anti-mCD16/32 antibody

Applications Tested/Suitable for anti-mCD16/32 antibody
Flow Cytometry (FC/FACS)
Application Notes for anti-mCD16/32 antibody
FC/FACS analysis: 0.5-1 ug/10^6 cells

Flow Cytometry (FC/FACS) of anti-mCD16/32 antibody

Figure-1: Cell surface flowcytometric analysis of mCD16/32 in Mouse splenocytes using 0.5 ug/10^6 cells of mCD16/32 (Clone: 2.4G2). Green represent Isotype control and Red represent Anti-CD16/32 antiboby (10-4126). Anti-Rat PE conjugated was used as secondary antibody.
Rat Anti-mCD16/32 Monoclonal Antibody – Cat# MBS668993

Flow Cytometry (FC/FACS) of anti-mCD16/32 antibody

Figure-2: Cell surface flowcytometric analysis of mCD16/32 in Mouse Lymph node cells using 0.5 ug/10^6 cells of mCD16/32 (Clone: 2.4G2). Green represent Isotype control and Red represent Anti-CD16/32 antiboby (10-4126). Anti-Rat PE conjugated was used as secondary antibody.
Rat Anti-mCD16/32 Monoclonal Antibody, Flow Cytometry (FC/FACS) – Cat# MBS668993

Other Notes

Small volumes of anti-mCD16/32 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for mCD16/32. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
low affinity immunoglobulin gamma Fc region receptor II-b isoform 2
NCBI Official Synonym Full Names
Fc receptor, IgG, low affinity IIb
NCBI Official Symbol
Fcgr2b
NCBI Official Synonym Symbols
CD32; Fcgr2; Fcr-2; Fcr-3; Ly-17; LyM-1; Lym-1; fcRII; FcgRII; Fcgr2a; Ly-m20; AI528646; Fc[g]RII; F630109E10Rik
UniProt Protein Name
Low affinity immunoglobulin gamma Fc region receptor II
UniProt Synonym Protein Names
Fc gamma receptor IIB; Fc-gamma RII; Fc-gamma-RIIB; FcRII; IgG Fc receptor II beta; Lymphocyte antigen 17; Ly-17; CD_antigen: CD32
UniProt Gene Name
Fcgr2
UniProt Synonym Gene Names
Fcgr2b; Ly-17; Fc-gamma RII; Fc-gamma-RIIB; FcRII; Ly-17
NCBI Protein Information
low affinity immunoglobulin gamma Fc region receptor II-b

UniProt Comments for mCD16/32

Receptor for the Fc region of complexed immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of antigen-antibody complexes from the circulation and modulation of antibody production by B-cells. Isoform IIB1 and isoform IIB1' form caps but fail to mediate endocytosis or phagocytosis. Isoform IIB2 can mediate the endocytosis of soluble immune complexes via clathrin-coated pits. Isoform IIB1 and isoform IIB2 can down-regulate B-cell, T-cell, and mast cell activation when coaggregated to B-cell receptors for AG (BCR), T-cell receptors for AG (TCR), and Fc receptors, respectively.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-mCD16/32 antibody

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