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CD137 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS669040

MBS669040 is an antibody targeting CD137. Also known as Monoclonal Antibody to CD137 (Clone: ABM3D3.2E8). Reactive in Human. Host: Mouse. More details

$210 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD137, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to CD137 (Clone: ABM3D3.2E8)
Product Gene Name
Product Synonym Gene Name
TNFRSF9
Product Synonym Names
Q07011; CD137 Tumor necrosis factor receptor superfamily member 9; 4-1BB ligand receptor; T-cell antigen 4-1BB homolog; T-cell antigen ILA
Clonality
Monoclonal
Isotype
IgG1, Kappa
Clone Number
ABM3D3.2E8
Host
Mouse
Species Reactivity
Human
Form/Format
25 ug in 50 ul/100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Purified
Protein G Chromatography
Preparation and Storage
Store the antibody at 4°C; stable for 6 months.
For long-term storage; store at -20°C.
Avoid repeated freeze and thaw cycles.
OMIM
U03397 mRNA
3D Structure
ModBase 3D Structure for Q07011
Antigen
CD137
Immunogen Information
A partial length recombinant protein of CD137 was used as the immunogen for this antibody.
Conjugation
Unconjugated

Product Categories/Family for anti-CD137 antibody

Applications Tested/Suitable for anti-CD137 antibody
Immunohistochemistry (IHC), FACS, Western Blot (WB)
Application Notes for anti-CD137 antibody
Western blot analysis: 4-6 ug/ml
Immunohistochemical Analysis: 2-4 ug/ml
Facs anaysis: 1-2 ug/10^6 Cells

Western Blot (WB) of anti-CD137 antibody

Figure-1: Westernblot analysis of CD137. Anti- CD137 (Clone: ABM3D3.2E8) was tested at 4 ug/ml on Jurkat, HepG2 and Molt-4.
Mouse Anti-CD137 Monoclonal Antibody – Cat# MBS669040

Immunohistochemistry (IHC) of anti-CD137 antibody

Figure-2: Immunohistochemical analysis of CD137. Anti-CD137 (Clone: ABM3D3.2E8) was used in Human Brain tissue at 2 ug/ml.
Mouse Anti-CD137 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS669040

Immunohistochemistry (IHC) of anti-CD137 antibody

Figure-3: Immunohistochemical analysis of CD137. Anti-CD137 (Clone: ABM3D3.2E8) was used in Human Tonsil tissue at 2 ug/ml.
Mouse Anti-CD137 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS669040

Testing Data(TD) of anti-CD137 antibody

Figure-1: Cell surface staining of PHA stimulated PBMC. Green represents isotype control, red represents Anti-CD137 (MBS669040). 1 ug antibody was used. Goat anti mouse PE was used as secondary antibody.
Mouse Anti-CD137 Monoclonal Antibody, Testing Data(TD) – Cat# MBS669040

Other Notes

Small volumes of anti-CD137 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD137. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
tumor necrosis factor receptor superfamily member 9
NCBI Official Synonym Full Names
TNF receptor superfamily member 9
NCBI Official Symbol
TNFRSF9
NCBI Official Synonym Symbols
ILA; 4-1BB; CD137; CDw137
UniProt Protein Name
Tumor necrosis factor receptor superfamily member 9
UniProt Synonym Protein Names
4-1BB ligand receptor; CDw137; T-cell antigen 4-1BB homolog; T-cell antigen ILA; CD_antigen: CD137
UniProt Gene Name
TNFRSF9
UniProt Synonym Gene Names
CD137; ILA
NCBI Protein Information
tumor necrosis factor receptor superfamily member 9

NCBI Summary for CD137

The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD137

Receptor for TNFSF9/4-1BBL. Possibly active during T cell activation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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