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NKp46 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS669244

MBS669244 is an antibody targeting NKp46. Also known as Monoclonal Antibody to Rat NKp46 (Clone: WEN23). Reactive in Rat. Host: Mouse. More details

$210 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NKp46, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to Rat NKp46 (Clone: WEN23)
Product Gene Name
Product Synonym Gene Name
Ncr1
Product Synonym Names
Natural cytotoxicity triggering receptor 1; Activating receptor 1; Lymphocyte antigen 94 homolog; NK receptor KILR-1; Natural killer cell p46-related protein; CD335
Clonality
Monoclonal
Isotype
IgG1 Kappa
Clone Number
WEN23
Host
Mouse
Species Reactivity
Rat
Form/Format
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Protein G Chromatography Purified
Preparation and Storage
Store the antibody at 4 degree C; stable for 6 months. For long-term storage; store at -20 degree C. Avoid repeated freeze and thaw cycles.
Molecular Weight
37,178 Da
3D Structure
ModBase 3D Structure for Q9Z0H5
Immunogen
NKp46
Immunogen Information
Recombinant rat NKp46 ectodomain coupled to the Fc portion of mouse IgG2b was used as the immunogen for this antibody.
Conjugation
Unconjugated

Product Categories/Family for anti-NKp46 antibody

Applications Tested/Suitable for anti-NKp46 antibody
Functional Assay, Immunoprecipitation (IP), Immunohistochemistry (IHC), Flow Cytometry (FC/FACS), Western Blot (WB)
Application Notes for anti-NKp46 antibody
FC/FACS: 1-2 ug/10^6 Cells
WB: 1-2 ug/ml
IP: 1-2 ug/ml

Flow Cytometry (FC/FACS) of anti-NKp46 antibody

Figure-1: Flow cytometry analysis of anti-NKp46 in IL-2-stimulated Rat NK cells. Black line represent anti-NKp46 (Clone:WEN23), dotted line represent Secondary antibody control.
Mouse Anti-NKp46 Monoclonal Antibody – Cat# MBS669244

Western Blot (WB) of anti-NKp46 antibody

Figure-2: Western blot analysis of anti-NKp46 in 293T cells transfected with a rat NKp46 expression construct and empty vector (EV) lysates at Non-reducing (NR) and reducing (R) condition.
Mouse Anti-NKp46 Monoclonal Antibody, Western Blot (WB) – Cat# MBS669244

of anti-NKp46 antibody

Figure-3: Immuno precipitation of anti-NKp46 from surface biotinylated, transiently transfected 293T cells using HRP-conjugated streptavidin under Non-reducing (NR) and reducing (R) conditions.
Mouse Anti-NKp46 Monoclonal Antibody – Cat# MBS669244

Product References and Citations for anti-NKp46 antibody

Ingunn H. Westgaard, Siri F. Berg, John T. Vaage, Lawrence L. Wang, Wayne M. Yokoyama, Erik Dissen, and Sigbjørn Fossum, Rat NKp46 activates natural killer cell cytotoxicity and is associated with Fc RI and CD3, September 8, 2004 as DOI:10.1189/jlb.0903428)

Other Notes

Small volumes of anti-NKp46 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NKp46. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
natural cytotoxicity triggering receptor 1
NCBI Official Synonym Full Names
natural cytotoxicity triggering receptor 1
NCBI Official Symbol
Ncr1
NCBI Official Synonym Symbols
Ly94; Nkp46; KILR-1; Nk-p46
UniProt Protein Name
Natural cytotoxicity triggering receptor 1
UniProt Synonym Protein Names
Activating receptor 1; rAR-1; Lymphocyte antigen 94 homolog; NK receptor KILR-1; NKACTR; Natural killer cell p46-related protein; NK-p46; NKp46; CD_antigen: CD335
UniProt Gene Name
Ncr1
UniProt Synonym Gene Names
Ar1; Kilr1; Ly94; rAR-1; NK-p46; NKp46
NCBI Protein Information
natural cytotoxicity triggering receptor 1

NCBI Summary for NKp46

has similarity to immunoglobulins; expressed in NK cells [RGD, Feb 2006]

UniProt Comments for NKp46

Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Organs/Tissues associated with anti-NKp46 antibody

 Organ/Tissue Name  Pubmed Publications
 Spleen Antibodies  >16 publications with NKp46 and Spleen
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