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TIGIT Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS669264

MBS669264 is an antibody targeting TIGIT. Also known as Monoclonal Antibody to Mouse TIGIT (Clone: 1G9). Reactive in Mouse. Host: Mouse. More details

$210 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TIGIT, Monoclonal Antibody
Full Product Name
Monoclonal Antibody to Mouse TIGIT (Clone: 1G9)
Product Gene Name
Product Synonym Names
T-cell immunoreceptor with Ig and ITIM domains; Tigit; P86176; T-cell immunoreceptor with Ig and ITIM domains; V-set and transmembrane domain-containing protein 3
Clonality
Monoclonal
Isotype
IgG1, Kappa
Clone Number
1G9
Host
Mouse
Species Reactivity
Mouse
Form/Format
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Protein G Chromatography Purified
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months. For long-term storage, store at -20 degree C. Avoid repeated freeze and thaw cycles.
Molecular Weight
26,959 Da
3D Structure
ModBase 3D Structure for P86176
Immunogen
T-cell immunoreceptor with Ig and ITIM domains
Conjugation
Unconjugated

Product Categories/Family for anti-TIGIT antibody

Applications Tested/Suitable for anti-TIGIT antibody
Flow Cytometry (FC/FACS), Western Blot (WB)
Application Notes for anti-TIGIT antibody
FC/FACS: 0.2-0.4 ug/10^6 Cells

Flow Cytometry (FC/FACS) of anti-TIGIT antibody

Figure 1: Cell surface staining of splenocytes stimulated with ConA + mIL2 for 3 days. Green represents mIgG1 isotope control, red represents Anti-mouse TIGIT (10-7651). 0.2 ug antibodies were used. Goat anti-mouse PE was used as secondary antibody.
Mouse Anti-TIGIT Monoclonal Antibody – Cat# MBS669264

Other Notes

Small volumes of anti-TIGIT antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TIGIT. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
T-cell immunoreceptor with Ig and ITIM domains
NCBI Official Synonym Full Names
T cell immunoreceptor with Ig and ITIM domains
NCBI Official Symbol
Tigit
NCBI Official Synonym Symbols
Vstm3
UniProt Protein Name
T-cell immunoreceptor with Ig and ITIM domains
UniProt Synonym Protein Names
V-set and transmembrane domain-containing protein 3
UniProt Gene Name
Tigit
UniProt Synonym Gene Names
Vstm3ImportedManual assertion inferred from database entriesiMGI:3642260
NCBI Protein Information
T-cell immunoreceptor with Ig and ITIM domains

UniProt Comments for TIGIT

Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T-cell activation by promoting the generation of mature immunoregulatory dendritic cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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