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SLC31A1 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS669314

MBS669314 is an antibody targeting SLC31A1. Also known as Monoclonal antibody to SLC31A1 (Clone: ABM5D89). Reactive in Human. Host: Mouse. More details

$210 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
SLC31A1, Monoclonal Antibody
Full Product Name
Monoclonal antibody to SLC31A1 (Clone: ABM5D89)
Product Gene Name
anti-SLC31A1 antibody
Product Synonym Names
Anti-SLC31A1 Antibody; ABM5D89; SLC31A1; Cancer Marker; SLC31A1; O15431; 1317; Anti SLC31A1 Antibody; SLC31A1 Antibody; Copper transporter 1; Solute carrier family 31 member 1; COPT1; CTR1
Clonality
Monoclonal
Isotype
IgG2b, kappa
Clone Number
ABM5D89
Host
Mouse
Species Reactivity
Human
Form/Format
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Protein G Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeated freeze and thaw cycles.
OMIM
603085
3D Structure
ModBase 3D Structure for O15431
Antigen
SLC31A1
Immunogen Information
Full length recombinant SLC31A1 protein was used as the immunogen for this antibody.

Product Categories/Family for anti-SLC31A1 antibody

Antibodies; Cancer Marker
Applications Tested/Suitable for anti-SLC31A1 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-SLC31A1 antibody
WB: 1-2 ug/ml
IHC: 5 ug/ml

Western Blot (WB) of anti-SLC31A1 antibody

Figure-1: Western blot analysis of SLC31A1. Anti-SLC31A1 antibody (Clone: ABM5D89) was tested at 1 ug/ml on (1) T98G and (2) THP1 lysates.
Mouse Anti-SLC31A1 Monoclonal Antibody – Cat# MBS669314

Immunohistochemistry (IHC) of anti-SLC31A1 antibody

Figure-2: Immunohistochemical analysis of SLC31A1 in Adenocarcinoma cell of human Stomach using Anti-SLC31A1 antibody (Clone: ABM5D89) at 5 ug/ml.
Mouse Anti-SLC31A1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS669314

Immunohistochemistry (IHC) of anti-SLC31A1 antibody

Figure-3: Immunohistochemical analysis of SLC31A1 in human Colon tissue using Anti-SLC31A1 antibody (Clone: ABM5D89) at 5 ug/ml.
Mouse Anti-SLC31A1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS669314

Immunohistochemistry (IHC) of anti-SLC31A1 antibody

Figure-4: Immunohistochemical analysis of SLC31A1 in human Kidney tissue using Anti-SLC31A1 antibody (Clone: ABM5D89) at 5 ug/ml.
Mouse Anti-SLC31A1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS669314

Immunohistochemistry (IHC) of anti-SLC31A1 antibody

Figure-5: Immunohistochemical analysis of SLC31A1 in human Placenta tissue using Anti-SLC31A1 antibody (Clone: ABM5D89) at 5 ug/ml.
Mouse Anti-SLC31A1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS669314

Immunohistochemistry (IHC) of anti-SLC31A1 antibody

Figure-6: Immunohistochemical analysis of SLC31A1 in human Prostate tissue using Anti-SLC31A1 antibody (Clone: ABM5D89) at 5 ug/ml.
Mouse Anti-SLC31A1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS669314

Immunohistochemistry (IHC) of anti-SLC31A1 antibody

Figure-7: Immunohistochemical analysis of SLC31A1 in human Skin tissue using Anti-SLC31A1 antibody (Clone: ABM5D89) at 5 ug/ml.
Mouse Anti-SLC31A1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS669314

Immunohistochemistry (IHC) of anti-SLC31A1 antibody

Figure-8: Immunohistochemical analysis of SLC31A1 in human Stomach tissue using Anti-SLC31A1 antibody (Clone: ABM5D89) at 5 ug/ml.
Mouse Anti-SLC31A1 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS669314

Other Notes

Small volumes of anti-SLC31A1 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC31A1. It may not necessarily be applicable to this product.

NCBI GI #
4507015
NCBI GeneID
1317
NCBI Accession #
NP_001850.1
UniProt Primary Accession #
O15431
UniProt Related Accession #
O15431
GenBank Nucleotide #
NP_001850.1
NCBI Official Full Name
high affinity copper uptake protein 1
NCBI Official Synonym Full Names
solute carrier family 31 member 1
NCBI Official Symbol
SLC31A1
NCBI Official Synonym Symbols
CTR1; COPT1
UniProt Protein Name
High affinity copper uptake protein 1
UniProt Synonym Protein Names
Copper transporter 1; hCTR1; Solute carrier family 31 member 1
Protein Family
High affinity copper uptake protein
UniProt Gene Name
SLC31A1
UniProt Synonym Gene Names
COPT1; CTR1; hCTR1
UniProt Entry Name
COPT1_HUMAN
NCBI Protein Information
high affinity copper uptake protein 1

NCBI Summary for SLC31A1

The protein encoded by this gene is a high-affinity copper transporter found in the cell membrane. The encoded protein functions as a homotrimer to effect the uptake of dietary copper. [provided by RefSeq, Aug 2011]

UniProt Comments for SLC31A1

SLC31A1: High-affinity, saturable copper transporter involved in dietary copper uptake. Belongs to the copper transporter (Ctr) (TC 1.A.56) family. SLC31A subfamily.

Protein type: Membrane protein, integral; Transporter, SLC family; Membrane protein, multi-pass; Transporter

Chromosomal Location of Human Ortholog: 9q32

Cellular Component: recycling endosome; cell soma; integral to plasma membrane; late endosome; plasma membrane

Molecular Function: copper ion transmembrane transporter activity; copper uptake transmembrane transporter activity

Biological Process: cellular copper ion homeostasis; multidrug transport; copper ion transport; transmembrane transport
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Research Articles on SLC31A1

1. The loss of CTR1 resulted in a decrease in the level of COMMD1, XIAP, and NF-kappaB. Differently, the DMT1 deficiency induced increase of the COMMD1, HIF1alpha, and XIAP levels.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-SLC31A1 antibody

 Reference Product  PubMed Publications
 ATP7A antibody  >30 publications with SLC31A1 and ATP7A
 ATP7B antibody  >23 publications with SLC31A1 and ATP7B
 ATOX1 antibody  >6 publications with SLC31A1 and ATOX1
 SP1 antibody  >4 publications with SLC31A1 and SP1

Pathways associated with anti-SLC31A1 antibody

 Products by Pathway  Pathway Diagram
 Metal Ion SLC Transporters Pathway antibodies  Metal Ion SLC Transporters Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 Mineral Absorption Pathway antibodies  Mineral Absorption Pathway Diagram
 SLC-mediated Transmembrane Transport Pathway antibodies  SLC-mediated Transmembrane Transport Pathway Diagram
 Transmembrane Transport Of Small Molecules Pathway antibodies  Transmembrane Transport Of Small Molecules Pathway Diagram
 Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway antibodies  Transport Of Glucose And Other Sugars, Bile Salts And Organic Acids, Metal Ions And Amine Compounds Pathway Diagram

Diseases associated with anti-SLC31A1 antibody

 Disease Name  Pubmed Publications
 Ovarian Neoplasms Antibodies  >14 publications with SLC31A1 and Ovarian Neoplasms
 Nervous System Diseases Antibodies  >13 publications with SLC31A1 and Nervous System Diseases
 Disease Models, Animal Antibodies  >7 publications with SLC31A1 and Disease Models, Animal
 Liver Diseases Antibodies  >6 publications with SLC31A1 and Liver Diseases
 Intellectual Disability Antibodies  >5 publications with SLC31A1 and Intellectual Disability
 Neoplasms, Experimental Antibodies  >4 publications with SLC31A1 and Neoplasms, Experimental
 Breast Neoplasms Antibodies  >2 publications with SLC31A1 and Breast Neoplasms
 Liver Neoplasms Antibodies  >2 publications with SLC31A1 and Liver Neoplasms
 Kidney Diseases Antibodies  >2 publications with SLC31A1 and Kidney Diseases
 Anemia Antibodies  >2 publications with SLC31A1 and Anemia

Organs/Tissues associated with anti-SLC31A1 antibody

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >17 publications with SLC31A1 and Blood
 Brain Antibodies  >13 publications with SLC31A1 and Brain
 Liver Antibodies  >11 publications with SLC31A1 and Liver
 Intestine Antibodies  >10 publications with SLC31A1 and Intestine
 Embryonic Tissue Antibodies  >7 publications with SLC31A1 and Embryonic Tissue
 Kidney Antibodies  >6 publications with SLC31A1 and Kidney
 Lung Antibodies  >5 publications with SLC31A1 and Lung
 Mammary Gland Antibodies  >5 publications with SLC31A1 and Mammary Gland
 Nerve Antibodies  >3 publications with SLC31A1 and Nerve
 Vascular Antibodies  >3 publications with SLC31A1 and Vascular
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