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KLF8 Antibody – Rabbit Polyclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS669342

MBS669342 is an antibody targeting KLF8. Also known as Polyclonal Antibody to KLF8. Reactive in Human. Host: Rabbit. More details

$200 / 0.025 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
KLF8, Polyclonal Antibody
Full Product Name
Polyclonal Antibody to KLF8
Product Gene Name
Product Synonym Names
Anti-KLF8 Antibody; Stem Cells; O95600; KLF8; 11279; Antibody to KLF8; Anti-KLF8 antibody; KLF8 antibody; Basic krueppel-like factor 3; Zinc finger protein 741; BKLF3; ZNF741
Clonality
Polyclonal
Isotype
IgG
Host
Rabbit
Species Reactivity
Human
Form/Format
100 ug in 200 ul PBS containing 0.05% BSA and 0.05% sodium azide. Sodium azide is highly toxic.
Purity/Purification
Protein A Chromatography
Preparation and Storage
Store the antibody at 4 degree C, stable for 6 months.
For long-term storage, store at -20 degree C.
Avoid repeat freezing and thawing.
OMIM
300286
3D Structure
ModBase 3D Structure for O95600
Antigen
KLF8
Immunogen Information
A partial length recombinant KLF8 protein (amino acids 15-235) was used as the immunogen for this antibody.

Product Categories/Family for anti-KLF8 antibody

Applications Tested/Suitable for anti-KLF8 antibody
Western Blot (WB)
Application Notes for anti-KLF8 antibody
WB: 0.1-0.5 ug/ml

Western Blot (WB) of anti-KLF8 antibody

Figure-1: Western blot analysis of KLF8. Anti-KLF8 antibody (11-12039) was used at 0.1 ug/ml on HepG2 lysate.
Rabbit Anti-KLF8 Polyclonal Antibody – Cat# MBS669342

Other Notes

Small volumes of anti-KLF8 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for KLF8. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
NCBI Official Full Name
Krueppel-like factor 8
NCBI Official Synonym Full Names
Kruppel like factor 8
NCBI Official Symbol
KLF8
NCBI Official Synonym Symbols
BKLF3; ZNF741
UniProt Protein Name
Krueppel-like factor 8
UniProt Synonym Protein Names
Basic krueppel-like factor 3; Zinc finger protein 741
Protein Family
UniProt Gene Name
KLF8
UniProt Synonym Gene Names
BKLF3; ZNF741
UniProt Entry Name
KLF8_HUMAN
NCBI Protein Information
Krueppel-like factor 8

NCBI Summary for KLF8

This gene encodes a protein which is a member of the Sp/KLF family of transcription factors. Members of this family contain a C-terminal DNA-binding domain with three Kruppel-like zinc fingers. The encoded protein is thought to play an important role in the regulation of epithelial to mesenchymal transition, a process which occurs normally during development but also during metastasis. A pseudogene has been identified on chromosome 16. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2009]
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UniProt Comments for KLF8

KLF8: Transcriptional repressor and activator. Binds to CACCC- boxes promoter elements. Also binds the GT-box of cyclin D1 promoter and mediates cell cycle progression at G(1) phase as a downstream target of focal adhesion kinase (FAK). Belongs to the Sp1 C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein; Transcription factor; DNA-binding

Chromosomal Location of Human Ortholog: Xp11.21

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; regulation of transcription, DNA-dependent
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-KLF8 antibody

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