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CD23 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS670334

MBS670334 is an antibody targeting CD23/FCeRII-PE. Also known as Mouse Anti-Human CD23/FCeRII-PE. Reactive in Human. Host: Mouse. More details

$375 / 100 Tests +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD23/FCeRII-PE, Monoclonal Antibody
Full Product Name
Mouse Anti-Human CD23/FCeRII-PE
Product Synonym Names
Mouse Anti-Human CD23 (FcåRII)
Clonality
Monoclonal
Isotype
IgG3
Clone Number
Tü1
Host
Mouse
Species Reactivity
Human
Form/Format
R-phycoerythrin (R-PE) Conjugate
Specificity
Human CD23
CD23 is a 45 kDa type II integral membrane glycoprotein that is the low affinity receptor for IgE. It also binds to CD21, and the alpha chains of CD11b and CD11c. It is expressed by B cells and monocytes and, weakly, on T cells, follicular dendritic cells, eosinophils, NK cells, Langerhans cells and platelets. It is upregulated in response to B cell activation, CD40 ligation, or in response to IL-4 or IL-13. CD23 is responsible for regulation of IgE synthesis and may play a role in antigen presentation by B cells and follicular dendritic cells by interacting with CD40.1-7
Preparation and Storage
The R-phycoerythrin (R-PE) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
Characterization
To insure lot-to-lot consistency, each batch of product is tested by flow cytometry to conform with the characteristics of a standard reference reagent.
Warning
Reagents contain sodium azide which is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Applications Tested/Suitable for anti-CD23/FCeRII-PE antibody
Flow Cytometry, Immunohistochemistry (Frozen sections), Immunoprecipitation
Application Notes for anti-CD23/FCeRII-PE antibody
Flow Cytometry: 10 uL/10^6 cells

Product References and Citations for anti-CD23/FCeRII-PE antibody

1. McMichael, A.K., P.C.L. Beverly, S. Cobbold, M.J. Crumpton, W. Gilks, F.M. Gotch, N. Hogg, M. Horton, N. Ling, I.C.M. MacLennan, D.Y. Mason, C. Milstein, D. Spiegelhalter, and H. Waldmann, eds. 1987. Leukocyte Typing III: White Cell Differentiation Antigens, Oxford University Press, Oxford.
2. Knapp, W., B. Dorken, W.R. GIlks, E.P. Rieber, R.E. Schmidt, H. Stein, A.E.G.K. Von dem Borne, eds. 1989. Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, Oxford.
3. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD23 Section, Academic Press, New York, p. 189.
4. Gordon, J. 1991. Clin. Exp. Immunol. 86:356.
5. Bonnefoy, J.-Y, S. Lecoanet-Henchoz, J.P. Aubry, J.F. Gauchat, and P. Graber. 1995. Curr. Opin. Immunol. 7:355.
6. Bonnefoy, J.-Y., C. Plater-Zyberk, S. Lecoanet-Henchoz, J.-F. Gauchat, J.-P. Aubry, and P. Graber. 1996. Immunol. Today 17:418.
7. Lamers, M.C., and P. Yu, 1995. Immunol. Rev. 148:71.

Other Notes

Small volumes of anti-CD23/FCeRII-PE antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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