Cd11a (LFA-1 Alpha) Antibody – Mouse Monoclonal

Monoclonal

Mouse IgG2a

38

Mouse

Human

Low Endotoxin, Azide - Free (LE/AF)

Human CD11a (LFA-1 alpha)
CD11a, also known as leukocyte function-associated antigen-1 (LFA-1 alpha), represents the 180 kDa integrin alpha L subunit which combines with the CD18 beta 2 integrin subunit to form the alpha L beta 2 integrin heterodimer. It is expressed on lymphocytes, granulocytes, monocytes, and macrophages and is upregulated on activated T cells. CD11a/LFA-1 alpha mediates adhesion of lymphocytes to vascular endothelium and is involved in costimulation.1-5

The purified antibody (UNLB) is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.2. No preservatives or amine-containing buffer salts added. Store at 2- 8 degree C.
The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The biotin (BIOT) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The R-phycoerythrin (R-PE), allophycocyanin (APC), and Spectral Red (SPRD) conjugates are supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
The low endotoxin/azide-free antibody is supplied as 0.1 mg purified immunoglobulin in 0.2 mL of PBS; aliquot and freeze upon receipt.
Protect conjugated forms from light. Reagents are stable for the period shown on the label if stored as directed.

To insure lot to lot consistency, each batch of product is tested by flow cytometry to conform with the characteristics of a standard reference reagent.