Mouse Anti-NDUFA2 Monoclonal Antibody – Cat# MBS674213

NDUFA2 Antibody – Mouse Monoclonal

Name: NDUFA2 Antibody; Monoclonal; Mouse; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS674213
Price: 405 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS674213

MBS674213 is an antibody targeting NDUFA2. Also known as Mouse Anti-Human CD14-SPRD. Reactive in Human. Host: Mouse. More details

$405 / 100 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD14 (NDUFA2), Monoclonal Antibody

Full Product Name

Mouse Anti-Human CD14-SPRD

Product Gene Name

anti-NDUFA2 antibody

Product Synonym Names

Mouse Anti-Human CD14 - SpectralRed-Labeled; Mouse Anti-Human CD14

Clonality

Monoclonal

Isotype

Mouse IgG2a

Clone Number

UCHM-1

Host

Mouse

Species Reactivity

Human

Form/Format

Spectral Red (SPRD) Conjugate

Specificity

Human CD14
CD14 is a 53-55 kDa glycosphosphatidylinositol (GPI)-anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.1-4

Preparation and Storage

The purified (UNLB) antibody is supplied as 0.1 mg purified immunoglobulin in 1.0 mL of 100 mM borate buffered saline, pH 8.0. Store at 2-8 degree C.
The fluorescein (FITC) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The biotin (BIOT) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3. Store at 2-8 degree C.
The R-phycoerythrin (R-PE) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
The Spectral Red (SPRD) conjugate is supplied as 100 tests in 1.0 mL of PBS/NaN3 and a stabilizing agent. Store at 2-8 degree C. Do not freeze!
Protect conjugated forms from light. Reagents are stable for the period shown on the label if stored as directed.

Molecular Weight

10,922 Da

Chromosome Location

Chromosome: 5; NC_000005.9 (140024948..140027370, complement). Location: 5q31.2

OMIM

602137

3D Structure

ModBase 3D Structure for O43678

Characterization

To insure lot to lot consistency, each batch of product is tested by flow cytometry to conform with the characteristics of a standard reference reagent.

Applications Tested/Suitable for anti-NDUFA2 antibody

Flow Cytometry; Immunohistochemistry (Acetone Fixed/Frozen Sections); Immunoprecipitation

Application Notes for anti-NDUFA2 antibody

Flow Cytometry Suggested Dilution: 10 uL/10^6 cells

Product References and Citations for anti-NDUFA2 antibody

1. Knapp, W., B. Dorken, W.R. GIlks, E.P. Rieber, R.E. Schmidt, H. Stein, A.E.G.K. Von dem Borne, eds. 1989. Leukocyte Typing IV: White Cell Differentiation Antigens, Oxford University Press, Oxford.
2. Barclay, A.N., M.H. Brown, S.K.A. Law, A.J. McKnight, M.G. Tomlinson, and P.A. van der Merwe, eds. 1997. The Leukocyte Antigens Facts Book, 2nd Edition, CD14 Section, Academic Press, New York, p. 169.
3. Hogg, N., S. MacDonald, M. Slusarenko, and P.C. Beverley. 1984. Immunol. 53:753.
4. Stocks, S.C., M. Albrechtsen, and M.A. Kerr. 1990. Biochem. J. 268:275.

Other Notes

Small volumes of anti-NDUFA2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NDUFA2. It may not necessarily be applicable to this product.

NCBI GI #

48146149

NCBI GeneID

4695

UniProt Primary Accession #

O43678

UniProt Secondary Accession #

Q6IAY8

UniProt Related Accession #

O43678

NCBI Official Full Name

CD14

NCBI Official Synonym Full Names

NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa

NCBI Official Symbol

NDUFA2

NCBI Official Synonym Symbols

B8; CD14; CIB8

UniProt Protein Name

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2

UniProt Synonym Protein Names

Complex I-B8; CI-B8; NADH-ubiquinone oxidoreductase B8 subunit

Protein Family

Monocyte differentiation antigen

UniProt Gene Name

NDUFA2

UniProt Entry Name

NDUA2_HUMAN

NCBI Protein Information

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 2; OTTHUMP00000159890; OTTHUMP00000223709; complex I B8 subunit; NADH-ubiquinone oxidoreductase subunit CI-B8

NCBI Summary for NDUFA2

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.

UniProt Comments for NDUFA2

Function: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Subunit structure: Complex I is composed of 45 different subunits.

Subcellular location: Mitochondrion inner membrane; Peripheral membrane protein; Matrix side.

Research Articles on NDUFA2

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-NDUFA2 antibody

Products by Pathway	Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Electron Transport Chain Pathway antibodies	Electron Transport Chain Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Oxidative Phosphorylation Pathway antibodies	Oxidative Phosphorylation Pathway Diagram
Parkinson's Disease Pathway antibodies	Parkinson's Disease Pathway Diagram

Diseases associated with anti-NDUFA2 antibody

Disease Name	Pubmed Publications
Leigh Disease Antibodies	>1 publications with NDUFA2 and Leigh Disease

Organs/Tissues associated with anti-NDUFA2 antibody

Organ/Tissue Name	Pubmed Publications
Muscle Antibodies	>1 publications with NDUFA2 and Muscle
Skin Antibodies	>1 publications with NDUFA2 and Skin