Bone Morphogenetic Protein 10 (BMP10) ELISA Kit for Rabbit

Name: Rabbit BMP10 ELISA Kit; Bone Morphogenetic Protein 10; MyBioSource
Brand: MyBioSource
SKU: MBS006752
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS006752

MBS006752 is a ready-to-use microwell, strip-or-full plate ELISA (enzyme-linked immunosorbent assay) Kit for analyzing the presence of the Bone Morphogenetic Protein 10 (BMP10) ELISA Kit target analytes in biological samples. The concentration gradients of… More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

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Product Overview

Online Datasheet in PDF

Product Name

Bone Morphogenetic Protein 10 (BMP10), ELISA Kit

Full Product Name

Rabbit Bone Morphogenetic Protein 10 ELISA Kit

Product Gene Name

BMP10 elisa kit

Species Reactivity

Rabbit

Assay Type

Sandwich

Preparation and Storage

Store all reagents at 2-8 degree C

Molecular Weight

48,047 Da

Chromosome Location

Chromosome: 2; NC_000002.11 (69092613..69098649, complement). Location: 2p13.3

OMIM

608748

3D Structure

ModBase 3D Structure for O95393

Other Notes

Small volumes of BMP10 elisa kit vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BMP10. It may not necessarily be applicable to this product.

NCBI GI #

7656928

NCBI GeneID

27302

NCBI Accession #

NP_055297.1

UniProt Primary Accession #

O95393

UniProt Secondary Accession #

Q53R17; Q6NTE0

UniProt Related Accession #

O95393

GenBank Nucleotide #

NM_014482.1

NCBI Official Full Name

bone morphogenetic protein 10 preproprotein

NCBI Official Synonym Full Names

bone morphogenetic protein 10

NCBI Official Symbol

BMP10

UniProt Protein Name

Bone morphogenetic protein 10

Protein Family

Bone morphogenetic protein

UniProt Gene Name

BMP10

UniProt Synonym Gene Names

BMP-10

UniProt Entry Name

BMP10_HUMAN

NCBI Protein Information

bone morphogenetic protein 10

NCBI Summary for BMP10

The protein encoded by this gene is a member of the TGF-beta family of growth factors. Data suggest that the similar protein in mouse plays an important role in trabeculation of the embryonic heart. In human, this protein may signal through receptor serine/threonine kinases. [provided by RefSeq, Jul 2008]

UniProt Comments for BMP10

BMP10: Required for maintaining the proliferative activity of embryonic cardiomyocytes by preventing premature activation of the negative cell cycle regulator CDKN1C/p57KIP and maintaining the required expression levels of cardiogenic factors such as MEF2C and NKX2-5. Acts as a ligand for ACVRL1/ALK1, BMPR1A/ALK3 and BMPR1B/ALK6, leading to activation of SMAD1, SMAD5 and SMAD8 transcription factors. Inhibits endothelial cell migration and growth. Belongs to the TGF-beta family.

Protein type: Secreted, signal peptide; Secreted

Chromosomal Location of Human Ortholog: 2p13.3

Cellular Component: extracellular space; cell surface; cytoplasm; extracellular region; Z disc

Molecular Function: receptor serine/threonine kinase binding; protein binding; growth factor activity; telethonin binding; hormone activity; cytokine activity; transforming growth factor beta receptor binding

Biological Process: adult heart development; extracellular matrix organization and biogenesis; atrial cardiac muscle morphogenesis; positive regulation of transcription, DNA-dependent; ventricular cardiac muscle cell development; activin receptor signaling pathway; cardiac muscle cell proliferation; sarcomere organization; regulation of apoptosis; BMP signaling pathway; regulation of MAPKKK cascade; ventricular cardiac muscle morphogenesis; negative regulation of cell growth; cell adhesion; negative regulation of cell migration; positive regulation of cardiac muscle cell proliferation

Research Articles on BMP10

1. Low expression of bone morphogenetic protein-10 is associated with urothelial cancer of the bladder.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with BMP10 elisa kit

Reference Product	PubMed Publications
ACVRL1 elisa kit	>8 publications with BMP10 and ACVRL1
MYH7 elisa kit	>1 publications with BMP10 and MYH7
MYH6 elisa kit	>1 publications with BMP10 and MYH6
SMARCA4 elisa kit	>1 publications with BMP10 and SMARCA4
PARP1 elisa kit	>1 publications with BMP10 and PARP1
ATF3 elisa kit	>1 publications with BMP10 and ATF3
CDKN1C elisa kit	>1 publications with BMP10 and CDKN1C

Pathways associated with BMP10 elisa kit

Products by Pathway	Pathway Diagram
Elastic Fibre Formation Pathway antibodies	Elastic Fibre Formation Pathway Diagram
Extracellular Matrix Organization Pathway antibodies	Extracellular Matrix Organization Pathway Diagram
Heart Development Pathway antibodies	Heart Development Pathway Diagram
Molecules Associated With Elastic Fibres Pathway antibodies	Molecules Associated With Elastic Fibres Pathway Diagram

Diseases associated with BMP10 elisa kit

Disease Name	Pubmed Publications
Vascular Malformations Antibodies	>3 publications with BMP10 and Vascular Malformations
Fibrosis Antibodies	>2 publications with BMP10 and Fibrosis
Dysostoses Antibodies	>1 publications with BMP10 and Dysostoses
Necrosis Antibodies	>1 publications with BMP10 and Necrosis
Inflammation Antibodies	>1 publications with BMP10 and Inflammation
Neoplasm Metastasis Antibodies	>1 publications with BMP10 and Neoplasm Metastasis