Insulin Like Growth Factor Binding Protein 5 (IGFBP5) ELISA Kit for Pigeon

IGFBP5: IGF-binding proteins prolong the half-life of the IGFs and have been shown to either inhibit or stimulate the growth promoting effects of the IGFs on cell culture. They alter the interaction of IGFs with their cell surface receptors.

Protein type: Secreted, signal peptide; Cell cycle regulation; Secreted

Chromosomal Location of Human Ortholog: 2q35

Cellular Component: insulin-like growth factor binding protein complex; extracellular space; extracellular region

Molecular Function: protein binding; insulin-like growth factor I binding; fibronectin binding; insulin-like growth factor II binding

Biological Process: positive regulation of insulin-like growth factor receptor signaling pathway; mammary gland involution; hair follicle morphogenesis; negative regulation of smooth muscle cell proliferation; negative regulation of insulin-like growth factor receptor signaling pathway; glucose metabolic process; negative regulation of smooth muscle cell migration; signal transduction; glucose homeostasis; osteoblast differentiation; positive regulation of protein kinase B signaling cascade; cellular protein metabolic process; negative regulation of translation; striated muscle cell differentiation; negative regulation of osteoblast differentiation; skeletal muscle growth; regulation of cell growth; negative regulation of cell migration