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Phosphogluconate Dehydrogenase (L. Mesenteroides) (6-PGDH) Enzyme

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS682065

MBS682065 is an enzyme targeting 6-PGDH. Also known as Phosphogluconate Dehydrogenase (L. mesenteroides) (6-PGDH). More details

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Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Product Name
Phosphogluconate Dehydrogenase (L. mesenteroides) (6-PGDH), Enzyme
Full Product Name
Phosphogluconate Dehydrogenase (L. mesenteroides) (6-PGDH)
Product Gene Name
Product Synonym Names
Phosphogluconate Dehydrogenase (L. mesenteroides); 6-PGDH (L. mesenteroides)
Form/Format
Ammonium Sulfate
Preparation and Storage
Ammonium Sulfate suspension at 0-5 degree C
Molecular Weight
52,970 Da
3D Structure
ModBase 3D Structure for P00349
Specifications
6-phospho-D-gluconate: NADP+ 2-oxidoreductase (decarboxylating) (EC 1.1.1.44) from Leuconostoc mesenteroides
Contaminant
Glucose-6-phosphate dehydrogenase < 0.05%
Phosphoglucose isomerase < 0.01%
Hexokinase < 0.02%
Glutathione reductase < 0.005%
NADH oxidase < 0.005%

Specific Activity: > 30 U/mg protein (at 25 degree C and pH 7.5)
Reaction Equation
6-Phospho-D-gluconate + NAD(P)+= D-ribulose-5-phosphate + CO2 + NAD(P)H
Preparation
Ammonium Sulfate suspension

Product Categories/Family for 6-PGDH enzyme

Other Notes

Small volumes of 6-PGDH enzyme vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for 6-PGDH. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
6-phosphogluconate dehydrogenase, decarboxylating
NCBI Official Symbol
PGD
NCBI Official Synonym Symbols
6-PGDH
UniProt Protein Name
6-phosphogluconate dehydrogenase, decarboxylating
UniProt Gene Name
PGD
UniProt Entry Name
6PGD_SHEEP
NCBI Protein Information
6-phosphogluconate dehydrogenase, decarboxylating; 6-phosphogluconate dehydrogenase (decarboxylating)

UniProt Comments for 6-PGDH

Function: Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO2, with concomitant reduction of NADP to NADPH.

Catalytic activity: 6-phospho-D-gluconate + NADP+ = D-ribulose 5-phosphate + CO2 + NADPH.

Pathway: Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.

Subunit structure: Homodimer. Ref.5 Ref.6

Subcellular location: Cytoplasm

Sequence similarities: Belongs to the 6-phosphogluconate dehydrogenase family.

Sequence caution: The sequence described in Ref.2 differs from that shown. Reason: Incorrect CNBR peptide order. Many sequencing errors.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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