Rabbit Anti-CD3 Monoclonal Antibody – Cat# MBS684107

CD3 Antibody – Rabbit Monoclonal

Name: CD3 Antibody; Monoclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS684107
Price: 265 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS684107

MBS684107 is an antibody targeting CD3. Also known as Anti - CD3. Reactive in Human. Host: Rabbit. More details

$265 / 1 mL (RTU) +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD3, Monoclonal Antibody

Full Product Name

Anti - CD3

Product Gene Name

anti-CD3 antibody

Clonality

Monoclonal

Clone Number

N26-R

Host

Rabbit

Species Reactivity

Human

Specificity

Human

Preparation and Storage

Store at +4 degree C.

Molecular Weight

23,147 Da

Chromosome Location

Chromosome: 11; NC_000011.10 (118304580..118316175). Location: 11q23

OMIM

186830

3D Structure

ModBase 3D Structure for P07766

Immunogen

Peptide derived from cytoplasmic, C-terminal region of human CD3-epsilon chain

Storage Buffer

20 mM Tris-HCI, pH 8.0

Stabilizer

20 mg/ml BSA

Preservative

0.05% NaN3

ISO Certification

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Applications Tested/Suitable for anti-CD3 antibody

Immunohistochemistry (IHC) - Formalin/Paraffin

Application Notes for anti-CD3 antibody

IHC-P dilution 1:100 - 1:200; IHC-Fr application and dilution to be tested by the user

Other Notes

Small volumes of anti-CD3 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD3. It may not necessarily be applicable to this product.

NCBI GI #

1345708

NCBI GeneID

916

NCBI Accession #

P07766.2

UniProt Primary Accession #

P07766

UniProt Secondary Accession #

A8K997

UniProt Related Accession #

P07766

NCBI Official Full Name

T-cell surface glycoprotein CD3 epsilon chain

NCBI Official Synonym Full Names

CD3e molecule, epsilon (CD3-TCR complex)

NCBI Official Symbol

CD3E

NCBI Official Synonym Symbols

T3E; TCRE; IMD18

UniProt Protein Name

T-cell surface glycoprotein CD3 epsilon chain

UniProt Synonym Protein Names

T-cell surface antigen T3/Leu-4 epsilon chain

Protein Family

CD302 antigen

UniProt Gene Name

CD3E

UniProt Synonym Gene Names

T3E

UniProt Entry Name

CD3E_HUMAN

NCBI Protein Information

T-cell surface glycoprotein CD3 epsilon chain; CD3-epsilon; T-cell surface antigen T3/Leu-4 epsilon chain; CD3e antigen, epsilon polypeptide (TiT3 complex); T-cell antigen receptor complex, epsilon subunit of T3

NCBI Summary for CD3

The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women. [provided by RefSeq, Jul 2008]

UniProt Comments for CD3

Function: The CD3 complex mediates signal transduction.

Subunit structure: The TCR/CD3 complex of T-lymphocytes consists of either a TCR alpha/beta or TCR gamma/delta heterodimer coexpressed at the cell surface with the invariant subunits of CD3 labeled gamma, delta, epsilon, zeta, and eta. Ref.12 Ref.13

Subcellular location: Membrane; Single-pass type I membrane protein.

Sequence similarities: Contains 1 Ig-like (immunoglobulin-like) domain.Contains 1 ITAM domain.

Research Articles on CD3

1. ABCB1 homozygous 3435 TT carrier subjects showed the lowest Pgp activity compared with 3435 CT and CC carriers of renal transplant patients.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.