Rabbit Anti-Ki-67 Monoclonal Antibody – Cat# MBS684191

Ki-67 Antibody – Rabbit Monoclonal

Name: Ki-67 Antibody; Monoclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS684191
Price: 275 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS684191

MBS684191 is an antibody targeting Ki-67. Also known as Anti - Ki-67. Reactive in Human. Host: Rabbit. More details

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Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Product Name

Ki-67, Monoclonal Antibody

Full Product Name

Anti - Ki-67

Product Gene Name

anti-Ki-67 antibody

Clonality

Monoclonal

Clone Number

E18-E

Host

Rabbit

Species Reactivity

Human

Specificity

Human

Preparation and Storage

Store at +4 degree C.

Molecular Weight

358,694 Da

Chromosome Location

Chromosome: 10; NC_000010.11 (128096659..128126204, complement). Location: 10q26.2

OMIM

176741

3D Structure

ModBase 3D Structure for P46013

Immunogen

Peptide derived from N-terminal region of human Ki-67

Storage Buffer

20 mM Tris-HCI, pH 8.0

Stabilizer

20 mg/ml BSA

Preservative

0.05% NaN3

ISO Certification

Manufactured in an ISO 9001:2008 and ISO 13485:2003 Certified Laboratory.

Applications Tested/Suitable for anti-Ki-67 antibody

Immunohistochemistry (IHC) - Formalin/Paraffin, Immunocytochemistry (ICC)

Application Notes for anti-Ki-67 antibody

IHC-P dilution 1:100 - 1:200; IHC-Fr application and dilution to be tested by the user, Immunocytochemistry (ICC)

Other Notes

Small volumes of anti-Ki-67 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for Ki-67. It may not necessarily be applicable to this product.

NCBI GI #

118572663

NCBI GeneID

4288

NCBI Accession #

P46013.2

UniProt Primary Accession #

P46013

UniProt Secondary Accession #

Q5VWH2

UniProt Related Accession #

P46013

NCBI Official Full Name

Antigen KI-67

NCBI Official Synonym Full Names

marker of proliferation Ki-67

NCBI Official Symbol

MKI67

NCBI Official Synonym Symbols

KIA; MIB-1

UniProt Protein Name

Antigen KI-67

UniProt Gene Name

MKI67

UniProt Entry Name

KI67_HUMAN

NCBI Protein Information

antigen KI-67; proliferation-related Ki-67 antigen; antigen identified by monoclonal antibody Ki-67

NCBI Summary for Ki-67

This gene encodes a nuclear protein that is associated with and may be necessary for cellular proliferation. Alternatively spliced transcript variants have been described. A related pseudogene exists on chromosome X. [provided by RefSeq, Mar 2009]

UniProt Comments for Ki-67

Function: Thought to be required for maintaining cell proliferation.

Subunit structure: Interacts with KIF15. Binds through the FHA domain to NIFK. Part of a complex composed at least of ASCL2, C11orf30/EMSY, HCFC1, HSPA8, CCAR2, MATR3, MKI67, RBBP5, TUBB2A, WDR5 and ZNF335; this complex may have a histone H3-specific methyltransferase activity. Ref.4 Ref.5 Ref.13 Ref.19

Subcellular location: Nucleus. Nucleus › nucleolus. Chromosome. Note: Predominantly localized in the G1 phase in the perinucleolar region, in the later phases it is also detected throughout the nuclear interior, being predominantly localized in the nuclear matrix. In mitosis, it is present on all chromosomes. Ref.20

Developmental stage: Expression of this antigen occurs preferentially during late G1, S, G2 and M phases of the cell cycle, while in cells in G0 phase the antigen cannot be detected.

Sequence similarities: Contains 1 FHA domain.

Research Articles on Ki-67

1. We demonstrate that axillary lymph node involvement and high expression of Ki-67 are associated with poorer prognosis.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-Ki-67 antibody

Reference Product	PubMed Publications
BIRC5 antibody	>98 publications with Ki-67 and BIRC5
TOP2A antibody	>22 publications with Ki-67 and TOP2A
CDK1 antibody	>12 publications with Ki-67 and CDK1
MKI67IP antibody	>9 publications with Ki-67 and MKI67IP
CCNA2 antibody	>7 publications with Ki-67 and CCNA2
PRC1 antibody	>2 publications with Ki-67 and PRC1
KIF11 antibody	>1 publications with Ki-67 and KIF11
KIF15 antibody	>1 publications with Ki-67 and KIF15
NCAPG antibody	>1 publications with Ki-67 and NCAPG

Diseases associated with anti-Ki-67 antibody

Disease Name	Pubmed Publications
Neoplasms Antibodies	>9650 publications with Ki-67 and Neoplasms
Adenocarcinoma Antibodies	>2212 publications with Ki-67 and Adenocarcinoma
Breast Neoplasms Antibodies	>1660 publications with Ki-67 and Breast Neoplasms
Nervous System Diseases Antibodies	>1466 publications with Ki-67 and Nervous System Diseases
Neoplasm Metastasis Antibodies	>1108 publications with Ki-67 and Neoplasm Metastasis
Carcinoma, Squamous Cell Antibodies	>1011 publications with Ki-67 and Carcinoma, Squamous Cell
Adenoma Antibodies	>709 publications with Ki-67 and Adenoma
Hyperplasia Antibodies	>600 publications with Ki-67 and Hyperplasia
Colorectal Neoplasms Antibodies	>599 publications with Ki-67 and Colorectal Neoplasms
Neoplasms, Experimental Antibodies	>551 publications with Ki-67 and Neoplasms, Experimental

Organs/Tissues associated with anti-Ki-67 antibody

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>1813 publications with Ki-67 and Blood
Brain Antibodies	>1289 publications with Ki-67 and Brain
Vascular Antibodies	>1162 publications with Ki-67 and Vascular
Lymph Node Antibodies	>1153 publications with Ki-67 and Lymph Node
Lymph Antibodies	>1147 publications with Ki-67 and Lymph
Skin Antibodies	>902 publications with Ki-67 and Skin
Lung Antibodies	>676 publications with Ki-67 and Lung
Liver Antibodies	>632 publications with Ki-67 and Liver
Muscle Antibodies	>626 publications with Ki-67 and Muscle
Bone Antibodies	>558 publications with Ki-67 and Bone